My brother takes 450mg a day and gained weight. He takes it for bipolor. I have high anxity and PTSD. I take Prazosin 4mg. at night and it works wonders. While he has bipolor. Been on many things that made me worse and kinda scared to try this. My Dr told me its such a low does it wont effect my weight but I hear it will. That will made me even more sad when I have reacuring nigthmares that make me sad and hipervigalent at the same time already. Hope to hear from someone. Thanks
Has anyone taken 25mg. to 50mg of Seroquel and gained or lost weight?
Question posted by Deliarose on 17 Aug 2012
Last updated on 5 July 2023 by alcon1502
My Dr. has put me on 25mg of seoquel today one a day. Then might might raise it to 50mg. she says a hight dose would make my stuation worse.
I been on seroquel 50 for about 20 years. Recently I tried to reduced to 25 mg and cause me so anxiety so go back to 50 mg. At 25 mg is ok to me. Next time I ll I tried to cut 12.5 mg for a month and then set it at 25 mg. I have no problem with weight gain. Seroquel is strong medication.
Hello, for a long time (years) I was in much heavier daily dosis of Seroquel 350 mg to Help with my insomnia, I didn't gain weight nor did I loose... (Wish I did) .
After I was using it for a while my sleeping pattern changed and I was able to fall a sleep and stay asleep without taking the medication all the time.
After a few years of taking Seroquel I decided to stop with my PSY approval becau I was taking other strong meds and Susan want my kidneys to pay the price; and ever since I haven't taken it any more. Has been about 10 years since I've stopped taking it, Yes, Eventuality I became an insomniac again but such is life... (I kind of enjoy being an insomniac now)
I earned to play sudoku and helps me to fall asleep fast, also I work on my garden at midnight to get tired and that helps me too, LOL! Find something that helps you to relax.
Seroquel works very well and doesn't create a habit, at least for me it didn't. Good luck!
I've been taking 300mg/day for several years and haven't gained an ounce. Although some people gain weight (5-10% of users will gain 5lbs or more) Seroquel can also cause anorexia and weight loss.
You just don't see reviews from happy, thin people.
Every person has potentially different responses to the same dosage and medication. Unfortunately, doctors tend to go by what they perceive as the norm and often disregard the individual experience. Trust yourselves and try communicating with your doctors. Arm yourself with information from literature prior to any conversation. The literature does say that Seroquel can cause weight gain. It doesn’t for everybody but it can. It could also be involved in a rare but serious disorder called serotonin syndrome or neuroleptic malignant syndrome. Seroquel is often prescribed for major depression I believe as an off label use but it’s initial use was as an antipsychotic. It is so important that both you and your physician know what is being treated And what your side effects are regardless of whether that is something they have been aware of or not. Not being heard while using a serious drug where you may have serious side effects can have disastrous results.
I know this is late but I’m on the same set up with prazosin and seroquel different mg but would consider to be low and to help with the weight issue my doctor also prescribed metformin which helps the body process sugar as you’ll see it’s normally for diabetes if you research it but a ton of psychoactive and anxiety meds can affect weight so this may be something you could ask your doctor about. I hope this helps someone good luck!
It can cause weight gain, however, I would also be concerned about it causing short time memory loss.
I have been taking 50 mg at bedtime, for 1 year. Actually eating less, but have gained 27 lbs
I have been taking 25 mg to 50 mg at night for nine years I have not gained any weight and I am a diabetic so if I was gaining weight they would probably take the medication away from me as it would affect my control but I haven’t had any problems at all the first weeks I was on it I can remember being very worried about Gaining weight too. But it doesn’t bother me at all now at the beginning it kind of made me hungry and I think that’s how it happens but on this low dose it’s unlikely you would gain any weight either
I am on 150 mg and have been for a little over a month. I have absolutely no appetite until I take it and then I want to eat everything in sight. I take it at night and then go straight to bed. I have actually lost weight (about 5 pounds) on this medication. My stomach is a little bloated, but nothing too noticeable. I was terrified I was going to gain weight on this medication, but so far I haven't. The worst side effect I've had is that I have low energy. But it helps in so many ways so I don't plan to come off of it. My doctor told me that if I do notice weight gain I can start taking Topamax. I've used it before and with exercise and a healthy diet, it really does help. Don't worry about weight gain. If it makes you feel better, take it. You can't have a healthy body without a healthy mind.
I have been on 75 mg. now for about 9 years. I tried to stop taking it but could not sleep at all. I was warned by the pharmacist that being a diabetic this wasn't the best choice but what I found was long term nothing else worked and to be honest I weighed around 130 at the start of taking it and still weigh the same, so it did not effect me the way I worried that it would. I stay the same.
I hope that is a help to know that it seems to be dose dependent. When you get up to the higher doses like your brother has to take it seems to affect your appetite somehow but low doses I would not worry just take it and see for yourself. It does make you tired and you will get some sleep! Best of luck :)
I started at 50mg, didn't gain any weight. Bumped up to 100mg, gained maybe 5 pounds or so. Bumped up to 150mg and gained about 15 pounds. Now I've been on 200mg for about 5 months and have gained 40 FREAKING POUNDS. Before I started taking it I was 120 pounds and 23 years old. I was always very skinny and no matter how I ate I didn't gain weight, I didn't even exercise. Seroquel completely reversed my metabolism and now I eat very strict and still can't keep weight off haha. Oh well though, the benefits of seroquel outweigh the cons for me.
I’v been on seroquel 25mg for only a few months now and I can honestly say that this medication causes weight gain. I take it at night to help me sleep and as soon as it kicks in I’m constantly at the kitchen getting food, when I should be sleeping and it’s the sweet and salty food that I crave on this med.
I think its a combination of mental and physical... I have been on 600mg and I gained 100 lbs in 2 yrs. The cravings were terrible... but not just cravings. I ate even when I was full... continually. Got off of Seroquel and lost 95 lbs but had problems sleeping so I had the doc put me on 300mg... work or so I thought( I didnt eat like a horse) but I stopped losing weight. I work out and eat extremely healthy. Now the cravings are back. I am going to drop down to 150 mg to see if that helps if not I'm back to Trazodone but at a higher dose to see if I can sleep through the night.
Yes I have been on Seroquel for 2 years and have increased weight significantly with blood sugars and liver enzymes not right. I have only recently really read the side affects as presumed my GP would have said something as the weight gain has been causing my severe depression and anxiety worse. I also see that it can cause Reflux which my GP have sent me to specialist, given all sorts of tests - but NO-ONE has ever mentioned it maybe a side affect. Has anyone else suffered with Reflux, increased sweating, decreased strength and energy plus vision changes ?
I created this account just to comment on Seroquel and weight gain and loss. When I first started taking it, I gained 25 pounds in about 1 month. No joke. I was taking 100mg a day for anxiety.
I went down to 50mg just for sleep and the weight was still there. So I started cardio, 1 hour SIX times a week, weights at the gym 3 times a week, and basically starving myself. 800 calories a day. I lost 20 pounds in 3 months, but that was with excessive exercise, food restriction.
I recently tapered down to a 1/4 of a 25mg pill. Used a pill splitter, so 6. 25mg a night for sleep or I sometimes take 12.5mg.
I literally peed out 10 pounds of bloat in 2 weeks on this lower dose. No joke. I can see my cheekbones again and everyone I know has commented on how I look less puffy. A good portion of the seroquel weight gain was water retention for me.
I was also pre-diabetic on higher doses of seroquel, I no longer am.
No matter what people tell you, Seroquel DOES do something to your metabolism. I want to get off it completely, but I need sleep and haven't found something that works for me.
If you can lower your dose, I highly recommend it. I don't feel like I'm wearing a fat suit anymore! When weight comes on that quickly, it's an awful feeling :( Does a number on ones self esteem for sure.
I wish you all good luck in your journey.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.