Can amlodipine raise blood pressure?

Yes. Hard YES. Amlodipine can raise blood pressure. I was taking Chlorthalidone, 25 mg, 1X daily and Losartan 50mg, 2X daily. Blood pressure was well controlled, usually under 120/80. I was taken off of Chlorthalidone because it is suspected to be elevating my blood sugar. Chlorthalidone was replaced with Amlodipine and my blood pressure rocket shipped from under 120 / 80 to over 170 / 95. Back on Chlorthalidone. Amlodipine is dangerous. I am sure it works for most people, but for me it is a death sentence.

I was on 5mg amlodipine and 12.5mg metoprolol ( tablet cut in half ). The doctor increased the amlodipine to 10mg. I noticed the following :
- Increase in blood pressure
- Insomnia
- I have essential tremor, mostly in my left hand - shaking became very bad in my left hand and
started in my right

I stopped taking both amlodipine and metoprolol and started 10mg lisinopril with the following effects :
- Blood pressure normal
- Sleeping pattern restored
- Essential tremor improved, right hand is fine now

Lisinopril is not without its side effects but at least it does what it's supposed to do i.e. Reduce your blood pressure. Amlodipine appears to have negatively affected my nervous system resulting in an increase in BP and worsening essential tremor.

I will not be taking Amlodipine again.

130/80? And why in the world are you even on high blood pressure medication???
But yes, I get VERY hot on amlodipine. If I try to walk or clean the house, it’s like I’ve stuck my face in hot coals. I feel like it’s not helping me at all. My face has been hot all day today. Right now it’s kind of tapering off. Still hot to the touch though. It makes my blood pressure rise it seems to over 30 points; especially the top number. My typical without pills, is 140-150/80 maybe… and on pills, it’s 180!

I am finding significant spikes as well. It worked at the start(about one year ago) but no,even when taking half of the 5mg.BP remains elevated. After taking a full 5mg last night my reading this morning is 192/105.I have none of the other listed side effects...

Hi , I`m an internist doctor ,
Amlodipine is manufactured to lower your blood oressure by dilating your blood vessels OK
but in some people if there is more than accepted blood vessel dilatation by amlodipine , your sympathetic nerve is excited through pressure receptors in your carotid arteries called baroreceptors to send electric impulses to your dilated artery to stop dilatation and even to constrict leading to reverse amlodipine effect.
This of course is in small percentage of the treated patients whose their sympathetic drive is overactive , and this may be the only explanation to the reverse response happened in your blood pressure.

I was prescribed 2.5mg of Amlodipine and within 3 hours my BP went from 145/80 to 199/121!! I was also taking losartan. I reached out to my doctor and she said that was impossible and instructed me to double the dose immediately! Now I don’t know about anyone here but there’s no way I will double down on a drug that spiked my BP to 199/121. Instead I took my evening dose (5 hours early) of 50mg of Losartan and It took another 5 hours for my BP to come down to 145/82. To the person who found the study that discussed an increase in BP as a result of taking Amlodipine (within this thread), it would be great if you can post that link somewhere. Doctors need to do a better job listening to their patients instead of thinking we’re making this stuff up! I lost my grandmother and great grandmother of a stroke at the same age I am now. I can’t imagine the outcome had I blindly followed her advice. Be your own advocate!

I share your experience. Amlodipine can definitely be poison. Doctor gave me a prescription of this drug and my blood pressure rose 40 points after the first pill and the feeling was awful. My doctor didn't believe me. Checking similar cases by Google I found only one study telling about this problem with amlodipine, so I couldn't do anything but throw those pills away.

This site might save my life. I, too, started taking Amlodipine just 1 week ago. Since then, my blood pressure has been higher than it has ever been, and the day after I started on it, spiked to 163/84. I feel weak, dizzy, jittery, and my heart pounds. These are symptoms I've never had before. My GP of 12 years said my BP was normal. I'd been assigned to a cardiology PA with 2 years experience, never saw a cardiologist, and she's been calling all the shots--while my health declines. I'm going off Amlodipine immediately and plan to find a certified cardiologist for some actual "care."

I have used amlodipine in the past but it never raised my BP.

Anyway your BP is not really high enough to be on meds. You should try to lower it with diet and lifestyle changes and some supplements to keep your BP in check. Try garlic supplements or Hawthorne berry.

I have never taken blood pressure medicine before now. I am 41 years old and I just started taking a daily dose of 2.5mg of amlodipine besylate (this is actually the second dose). Before taking amlodipine besylate my blood pressure was 137/84 with heartrate at 53bpm. I took the drug and waited 30 minutes and rechecked my blood pressure. I was shocked to see that it increased to 168/97 with heartrate at 58bpm. I did some breathing exercises and rechecked in 30 minutes and I could not get it lower than 129/86. Usually, when I do the breathing exercises I can get my blood pressure down to 115/75. I don't think I will be using this drug anymore.

Wow Dr put me on this medication a month ago 5 mgs went for bp check 2 weeks later bp 172/93. She said take 10 mg check today 186/114. Wanted me to pay her 100 dollars for an office visit to change my medicine. Think I will just go back to my lisinopril

I went online to research the same situation and thanks teacher. I started amlodipine in addition to bisoprolol, which I have been on for some time, four weeks ago. Almost immediately my BP went from 125-130 to 145-150. I stuck with it for three weeks and took myself off. Four days later I am back down to 125. I restarted taking Ameal Peptide 3.5mg which has had a good stabilizing affect on my BP. I should have not stopped taking it. I am waiting to talk to my doctor. I hope this helps

I too experienced a noticeable spike in my bp after adding Amlodipine 5mg to Losartan 100mg. While taking Losartan alone, my bp would hang between 115/75-140/85. I guess this wasn't accept to my doctor, who then added the 5mg of Amlodipine. After only 1 week, my bp is hanging around 160/86. I was also almost unable to stay awake during the day. I stopped taking it today and went back to just the Losartan. IMMEDIATELY, my bp was back down to about 125/80. I like that bp and will never take Amlodipine again. I hope you will at least talk to your doctor about discontinuing Amlodipine. Your side effects are off the chart. I'll say a pray for you, ThatTeacherGuy.

Hi ThatTeacherGuy. This medication is taken to help lower your blood pressure. Am I right? Wow the side effects are crazy eh? Other medications; even some vitamins; can have an interaction with Amlodipine. Does your doctor know everything you’re taking? Are you in any pain? I know from experience that pain can make your blood pressure go up. I know I probably didn’t help you any; but I hope you find out what’s going on. Take care and best wishes.
Cindy59