I have chronic insomnia. Ambien has stopped working because I've taken it for years. It gradually lost its effectiveness and i had to double up on doses to get a few hours sleep. Then I'd run out of pills whuch was a problem. So I'd substitute with lorazapam. But that stopped working as well. OTC's like dyphenhydramine do not work and actually make me jumpy. Melatonin does not work. All the little protocols, obviously I do, limit caffeine, darken room, etc. Etc. Is there something else I can ask my doctor for? Sleepless in NY.
What to do when Ambien stops working?
Question posted by rachel104 on 15 Jan 2018
Last updated on 11 June 2021 by Kat105
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13 Answers
My doctor added Mirtazapine 7.5 mg to my ambien cr. It does help me sleep but I feel hungover and drugged for a couple of hours after waking. I've been taking the ambien for years wish I knew how to get off.
I also had the same issue with Ambien. It only worked for maybe two weeks, and then even taking two 10mg pills did nothing. I went back on Trazodone and I take 200mg. It worked quite well for a while, but I was up all night last night, which happens occasionally. Like so many of us I have become somewhat resistant to both pain and sleep medication. I have been a chronic pain patient for many years and suffer from depression and anxiety as well. I know how difficult it is to deal with the pain/depression cycle, and my heart goes out to my fellow sufferers. I have had issues with insomnia since I was a child and it is so exhausting to be exhausted all the time. After reading everyone's posts I plan to ask about trying Belsomra, since I doubt adding additional Trazodone would be a good idea. Blessings to you all in the new year!
The lorazepam binds to the same benzodiazepine receptors as the ambien which it sounds like you now have a tolerance for. Diphenhydramine is an antihistamine H1 antagonist and some people get drowsy from that others get alert. trazodone an antidepressant but off label prescribed for sleep. Common side effects are nasal swelling and respiratory breathing difficulty so if that gets prescribed have someone with you. Some people take ltheanine to balance stimulation from caffeine ingested.
It is hard to out do a hypnotic especially when using it for years.
I am currently on enough sleep medicine to tranquilize a horse. Once my body got acclimated to the Ambien and it became ineffective I took a drug holiday for a month and tried Lunesta which worked well at first but then began to fail so we switched back to Ambien and Trazodone combo works much better. Good luck! Not being able to sleep really stinks
This may sound silly... but.
I am aware of the empty stomach in regards to ambien. However, if I "wash" my ambien down with a little bit of peanut butter, like on a 1/4 piece of bread, it seems to help me sleep.
I am also a restless legs person. For whatever reason, putting a few bars of soap next to my legs seems to alleviate the restless legs most of the time(I know... but I was so desperate the first time I heard of this solution I drove right to the store and could not believe it worked). When it doesn't, I rub my legs with aloe vera or Jergans ultra moisturizer. Sometimes I have to rub them several times, but the restlessness dissipates after each application.
Hi Rachel104,
I've taken almost everything for my insomnia from OTC AND Rx. When Ambien stopped working for me my Dr put me on Lunesta but it only worked like a month. It seemed closely related to Ambien. Then he put me on Belsomra. It's relatively new and insurances don't want to cover it unless you've tried all the others first. Anyway, I've been on it a year and still doing great. I even cut my dose in half. I strongly suggest this. Good luck. Insomnia is horrible!
I do have a lot a trouble fighting insomnia as well. Since I was a teenager I use to wait hours and hours on bed until I finally get to sleep. Now I have depression and everything is worsening. Last month I started sleeping about 3 hours a day or not sleeping at all. Then I started used Ambien CR. It worked like a dream, but only for the first two weeks. My doctor refused to change medication and, as I'm already on the higher dose of it, I'm just here, second day fully awake and looking at my ceiling.
Ambien has stopped working for me,Completely... i look terrible,and feel terrible... i was on 10 mgs,I feel like I got,Placebos,by mistake
I've never slept without a sleep aid before, not even as a baby. Benadryl, zquil, nyquil, melatonin, trazodone, lorazepam... you name it I've tried it. Did many different "cocktails" of drug combinations and they sort of worked for a little bit but ended up having no effect. I've had 2 doctors tell me they won't see me anymore because i'm a "lost cause" and sleep specialist refuse to see me. The longest time ive gone without any sleep is 2 months and 3 days (not exaggerating, it's awful). The only thing that has been helping so far has been taking 10mg of zolpidem (ambien) and 100mg of trazodone. It doesn't help all the time (especially if taken after food) but it has definitely helped me. Ambien alone doesn't have any effect on me (not even if I take 50mg that night) but there is something about ambien and trazodone together that seems to help.
Oh! And do NOT take Unisom OR benadryl if you are as severe as me with insomnia because it has the opposite effect on me. It will make you stay awake and make your limbs tingle and go numb and you'll be in so much pain and discomfort. I'm only a few months into trazodone and ambien so I'll update this comment in a few months.
I have been taking Ambien for about 10 years. The empty stomach was a problem. Then effectiveness was diminishing. I put tablet under my tongue to dissolve. More fully absorbs and acts faster.
I am also having the same issues as you all are describing. I have been on ambien for the last 10 years, started with 10mg and that worked for a lot of years, then about 3 years ago, I got a very stressful job and wasn't sleeping well, so I upped my own dose and start cutting pills and taking 15mg every night. I quickly realized my prescription was running out too soon, and the pharmacy wouldnt fill another script until the 30 days was up. So I had to drop my dose down to 12mg, and try to make it last that way. Its not working though, Im still running out as im only prescribed 30 pills of 10mg each every month. Im not sleeping, Im missing work, and I am a single mom of 2 boys to keep up with, which is VERY hard when im just dead exhausted all day everyday getting 4-5 broken hours day in and day out. I have had sleep studies, have been tested for sleep apnea and restless leg syndrome, dont have those. Been to therapy, dentists, ear nose throat doctors.
Im not sure where to turn as I feel like if this continues, i will loose my job and my sanity.
Anyone have thoughts on taking 10mg ambien with Valerian root or Benadryl?
I'm in the same boat... last night I took 10 mgs Ambien,5 Melatonins at 10 mgs a piece+++ Nyquil... i slept for 10 minutes
I have had chronic insomnia since '97..I have fibromyalgia. I have been taking ambien since 2001. Used to work like a charm. But over the years I have had to take a ''cocktail'' of different sleep meds. After ambien alone was not working well I took ambien with melatonin. ..5 mg. Years later I increased the melatonin. For quite some time I have been taking about 3/4 of an ambien,10 mg of melatonin and one generic Doxylamine tablet as a sleep med ''cocktail'' .. I am not recommending it... I am just saying what I take and have for at least the last year. I have to take it early in the evening. Not working as well as it did for a while. After so many years of insomnia and having a high tolerance for most meds I am wondering how long this is going to keep working for me. So I ended up here.
You can ask your doctor about trazadone. I've been on 10mg of ambien for 9 years. Still works fine as long as I take it on an empty stomach. Doc wants me off of Ambien, so tonight I'm trying the 50mg of trazadone. He said if it don't work that I can take half of an Ambien with it. Good luck. Remember, take it on an empty stomach.
Yes, indeed the empty stomach caveat. I get home late and have modest dinner. So I try to wait hours before taking the Ambien as not to waste it. You only get 30 so you only get so many attempts to get it to work. So as little as a saltine in my stomach and its over, I've wasted the pill. So hours later in the night I will try a,second pill and That will work for about 3 or four hours. Taking two at time on a completely empty stomach often works but these are all signs of it fading effects and then the stress of going 16 days and you have 4 pills left and nothing else works. My doctors make feel like I shouldn't be asking for sleeping pills. So I have been timid about asking for something else fearing they will take,away my Ambien forever. So that's why I'm asking folks here. Thank you so much for your reply. I will ask my doctor about this product, does it work as nice as Ambien back when first taking it?
trazodone helps me fall asleep but then I wake so congested. I can’t breath through my nose which means I no longer sleep.
Related topics
ambien, insomnia, sleep disorders, sleep, dosage, chronic, sleep disorder
Further information
- Ambien uses and safety info
- Ambien prescribing info & package insert (for Health Professionals)
- Side effects of Ambien (detailed)
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