I am taking 30 mg of mirtazapine per day. My psychiatrist wants to increase my dose to 60 mg. On the package insert of the drug it is written that the maximum dose is 45mg. I am afraid to take 60mg; Is there a reason why the instructions say that the maximum dose is 45 mg?
Thank you
Take 60 mg of mirtazapine per day?
Question posted by piazzolla on 17 Dec 2021
Last updated on 17 December 2021 by WildcatVet
Answers
WildcatVet
17 Dec 2021
Hi, piazzolla!
Clinical studies have only been performed on the maximum of 45mg and not on 60mg. It may be perfectly safe but your doctor is prescribing off-label.
If you decide to increase your dosage you might ask your doctor if you could titer the dose upwards... say to the 45mg maximum and see how you do before going up to the 60mg. You're looking for the lowest dose that controls your symptoms.
Also, doubling your dose all at once could cause new or increased side effects.
I'd take your concerns to your doctor...
Related topics
mirtazapine, dosage, psychiatry, drug
Further information
- Mirtazapine uses and safety info
- Mirtazapine prescribing info & package insert (for Health Professionals)
- Side effects of Mirtazapine (detailed)
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