20 years on fluoxetine. Long-term side effects? Feeling very sleepy, tired, lethargic?
Question posted by mexicansunrise on 1 June 2018
Last updated on 5 June 2018 by silly-girl
I've been on Prozac/fluoxetine since 1997 for adult-onset depression. Started at 20 mg/day and over the years I've reduced the dosage to 10 mg every other day.
My question is about the long-term effects of fluoxetine. I have been feeling extremely sleepy and lethargic for the past five years or so. I never seem to get enough sleep to feel rested. I wonder if the lack of energy and sluggishness might be a side-effect of being on the medication for 20+ years.
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
Answers
SI
silly-girl
5 June 2018
Trying "blood orange tea" could help getting over this condition; I will help you for body relaxation.
Votes: +0
WI
WildcatVet
1 June 2018
Hi, sunrise! Sorry about the copy/paste, but here's what I've found: "Considering the limited data available on long-term, selective serotonin reuptake inhibitor management, we report for the first time on two cases of late-onset adverse effects occurring 6 and 10 years after chronic-fluoxetine treatment in which patients experienced symptoms of restlessness, tension, agitation, and sleep disturbances." "The chronic use of antidepressants like Prozac could lead to changes in mood, and increased experience of agitation, anxiety, insomnia, restlessness, and nervousness, with the highest rates among people taking the highest doses [5]." It would seem to me that you're experiencing just the opposite effects. Have you had a thorough physical performed recently including blood work to check things like your Vitamin D and thyroid levels? Just to rule out any underlying causes? Another thing... antidepressants have a tendency to "poop out" and stop working after long term use. Could you, in fact, be feeling symptoms of depression? I'd talk to your doctor and get her/his professional advice. Best regards and good luck!