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Tilade Side Effects

Generic Name: nedocromil

Note: This document contains side effect information about nedocromil. Some of the dosage forms listed on this page may not apply to the brand name Tilade.

Some side effects of Tilade may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to nedocromil: inhalation aerosol powder

Along with its needed effects, nedocromil (the active ingredient contained in Tilade) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking nedocromil:

Less common
  • Abdominal pain
  • body aches or pain
  • chills
  • congestion
  • cough
  • dryness or soreness of throat
  • ear congestion
  • fever
  • hoarseness
  • increased wheezing, tightness in chest, or difficulty in breathing
  • loss of voice
  • nasal congestion
  • noisy breathing
  • runny nose
  • shortness of breath
  • sneezing
  • stuffy nose
  • tender, swollen glands in neck
  • trouble in swallowing
  • unusual tiredness or weakness
  • voice changes
  • Pain, stiffness, or swelling of joints

Some side effects of nedocromil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Headache
  • nausea or vomiting
  • sensation of warmth
  • throat irritation
  • tremor
  • unpleasant taste

For Healthcare Professionals

Applies to nedocromil: inhalation aerosol with adapter


Gastrointestinal side effects have included unpleasant taste which was reported in approximately 13% of patients receiving nedocromil (the active ingredient contained in Tilade) and resulted in drug withdrawal in up to 3%. Less commonly, nedocromil has caused nausea and vomiting (2% to 4%).


Throat irritation may be relieved by drinking water before and after inhalation of nedocromil (the active ingredient contained in Tilade) Use of a beta-2 agonist prior to nedocromil inhalation may relieve cough and bronchospasm.

Respiratory side effects have included cough and throat irritation in 6% to 7% of patients treated with nedocromil. Bronchospasm has been induced in 5% of patients.

Nervous system

Nervous system side effects have included headache in up to 6% of patients treated. Less commonly dizziness has been reported.


Hepatic side effects have included elevations of liver function tests (SGPT) in approximately 3% of patients treated with nedocromil (the active ingredient contained in Tilade)

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