Skelaxin Side Effects

Generic Name: metaxalone

Please note - some side effects for Skelaxin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Skelaxin - for the Consumer

Skelaxin

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Skelaxin:

Dizziness; drowsiness; headache; irritability; nausea; nervousness; upset stomach; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever, chills, or sore throat; unusual or severe tiredness or weakness; yellowing of the skin or eyes.

Skelaxin Side Effects - for the Professional

Skelaxin

The most frequent reactions to metaxalone include:

CNS: drowsiness, dizziness, headache, and nervousness or “irritability”;

Digestive: nausea, vomiting, gastrointestinal upset.

Other adverse reactions are:

Immune System: hypersensitivity reaction, rash with or without pruritus;

Hematologic: leukopenia; hemolytic anemia;

Hepatobiliary: jaundice.

Though rare, anaphylactoid reactions have been reported with metaxalone.

Side Effects by Body System

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and gastrointestinal upset have been reported.

Nervous system

Nervous system side effects including drowsiness, dizziness, headache, and nervousness or irritability have been reported.

Hematologic

Hematologic side effects including leukopenia and hemolytic anemia have been reported.

Hypersensitivity

Hypersensitivity side effects including a hypersensitivity reaction characterized by a light rash with or without pruritus have been reported.

Hepatic

Hepatic side effects including elevation in cephalin flocculation tests (without concurrent changes in other liver function parameters) and jaundice have been reported.

Other

Other side effects including a false-positive Benedict's tests (due to an unknown reducing substance) have been reported.

A glucose-specific test may be used to differentiate findings.

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