Skelaxin Side Effects

Generic name: metaxalone

Note: This document contains side effect information about metaxalone. Some of the dosage forms listed on this page may not apply to the brand name Skelaxin.

Some side effects of Skelaxin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to metaxalone: oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking metaxalone (the active ingredient contained in Skelaxin) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using metaxalone and call your doctor at once if you have any of these serious side effects:

• nausea, stomach pain, loss of appetite;

• low fever;

• dark urine, clay-colored stools; or

• jaundice (yellowing of the skin or eyes).

Less serious side effects of metaxalone may include:

• drowsiness, dizziness;

• feeling nervous or irritable;

• headache;

• mild nausea, vomiting, upset stomach; or

• skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to metaxalone: oral tablet

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and gastrointestinal upset have been reported.

Nervous system

Nervous system side effects including drowsiness, dizziness, headache, and nervousness or irritability have been reported.

Hematologic

Hematologic side effects including leukopenia and hemolytic anemia have been reported.

Hypersensitivity

Hypersensitivity side effects including a hypersensitivity reaction characterized by a light rash with or without pruritus have been reported.

Hepatic

Hepatic side effects including elevation in cephalin flocculation tests (without concurrent changes in other liver function parameters) and jaundice have been reported.

Other

Other side effects including a false-positive Benedict's tests (due to an unknown reducing substance) have been reported.

A glucose-specific test may be used to differentiate findings.

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