Skelaxin Side Effects
Generic name: metaxalone
Note: This document contains side effect information about metaxalone. Some of the dosage forms listed on this page may not apply to the brand name Skelaxin.
Some side effects of Skelaxin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to metaxalone: oral tablet
Along with its needed effects, metaxalone (the active ingredient contained in Skelaxin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking metaxalone:More common
- Abdominal or stomach pain
- back or leg pains
- black, tarry stools
- bleeding gums
- chest pain
- dark urine
- difficulty in breathing or swallowing
- fast heartbeat
- general body swelling
- loss of appetite
- nausea or vomiting
- painful or difficult urination
- pale skin
- shortness of breath
- skin itching, rash, or redness
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swelling of the face, throat, or tongue
- swollen glands
- unpleasant breath odor
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood
- yellowing of the eyes or skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- tightness in the chest
Some side effects of metaxalone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- stomach cramps
For Healthcare Professionals
Applies to metaxalone: oral tablet
Gastrointestinal side effects including nausea, vomiting, and gastrointestinal upset have been reported.
Nervous system side effects including drowsiness, dizziness, headache, and nervousness or irritability have been reported.
Hematologic side effects including leukopenia and hemolytic anemia have been reported.
Hypersensitivity side effects including a hypersensitivity reaction characterized by a light rash with or without pruritus have been reported.
Hepatic side effects including elevation in cephalin flocculation tests (without concurrent changes in other liver function parameters) and jaundice have been reported.
Other side effects including a false-positive Benedict's tests (due to an unknown reducing substance) have been reported.
A glucose-specific test may be used to differentiate findings.
More Skelaxin resources
- Skelaxin Prescribing Information (FDA)
- Skelaxin Consumer Overview
- Skelaxin Monograph (AHFS DI)
- Skelaxin Advanced Consumer (Micromedex) - Includes Dosage Information
- Skelaxin MedFacts Consumer Leaflet (Wolters Kluwer)
- Metaxalone Professional Patient Advice (Wolters Kluwer)
- Metaxalone Prescribing Information (FDA)
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