Skelaxin Side Effects

Generic Name: metaxalone

Note: This page contains side effects data for the generic drug metaxalone. It is possible that some of the dosage forms included below may not apply to the brand name Skelaxin.

It is possible that some side effects of Skelaxin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to metaxalone: oral tablet

As well as its needed effects, metaxalone (the active ingredient contained in Skelaxin) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking metaxalone, check with your doctor immediately:

More common
  • Abdominal or stomach pain
  • back or leg pains
  • black, tarry stools
  • bleeding gums
  • chest pain
  • chills
  • cough
  • dark urine
  • difficulty in breathing or swallowing
  • dizziness
  • fast heartbeat
  • fever
  • general body swelling
  • headache
  • itching
  • loss of appetite
  • nausea or vomiting
  • nosebleeds
  • painful or difficult urination
  • pale skin
  • rash
  • shortness of breath
  • skin itching, rash, or redness
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the face, throat, or tongue
  • swollen glands
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting of blood
  • yellowing of the eyes or skin
Rare
  • Hives
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • tightness in the chest
  • wheezing

Some metaxalone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Diarrhea
  • drowsiness
  • irritability
  • stomach cramps
  • vomiting

For Healthcare Professionals

Applies to metaxalone: oral tablet

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and gastrointestinal upset have been reported.

Nervous system

Nervous system side effects including drowsiness, dizziness, headache, and nervousness or irritability have been reported.

Hematologic

Hematologic side effects including leukopenia and hemolytic anemia have been reported.

Hypersensitivity

Hypersensitivity side effects including a hypersensitivity reaction characterized by a light rash with or without pruritus have been reported.

Hepatic

Hepatic side effects including elevation in cephalin flocculation tests (without concurrent changes in other liver function parameters) and jaundice have been reported.

Other

Other side effects including a false-positive Benedict's tests (due to an unknown reducing substance) have been reported.

A glucose-specific test may be used to differentiate findings.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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