Optimine Side Effects

Please note - some side effects for Optimine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects by Body System

Nervous system

Nervous system side effects have commonly included central nervous system depression with resulting drowsiness. Azatadine has also caused dizziness and affected coordination.

The drowsiness caused by azatadine may subside in some patients following prolonged use. Patients should be warned against driving, as well as concomitant ingestion of alcohol and other sedative-hypnotic drugs, while taking azatadine.

At dosages above what is normally recommended, dystonic reactions have occurred.

Gastrointestinal

Gastrointestinal side effects have included dry mouth and constipation due to anticholinergic effects. Patients have also experienced epigastric distress and nausea. Increased appetite has been reported.

Cardiovascular

Cardiovascular side effects have included hypotension, tachycardia, and palpitations.

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes due to cholinergic blockade.

Genitourinary

Genitourinary side effects have included dysuria, urinary hesitancy, decrease in urinary flow, and in rare cases, acute urinary retention. These urinary tract effects may have been due to azatadine's anticholinergic effects.

Hematologic

Hematologic side effects have included reports of bone marrow suppression, thrombocytopenia, and aplastic anemia.

Respiratory

Respiratory side effects have included thickening of bronchial secretions.

Hypersensitivity

Hypersensitivity reactions to azatadine have included rash and urticaria.

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