Optimine Side Effects

Generic Name: azatadine

Note: This document contains side effect information about azatadine. Some of the dosage forms listed on this page may not apply to the brand name Optimine.

Some side effects of Optimine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to azatadine: oral tablet

Stop taking azatadine (the active ingredient contained in Optimine) and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take azatadine and talk to your doctor if you experience

  • sleepiness, fatigue, or dizziness;

  • headache;

  • dry mouth; or

  • difficulty urinating or an enlarged prostate.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to azatadine: oral tablet

Nervous system

Nervous system side effects have commonly included central nervous system depression with resulting drowsiness. Azatadine (the active ingredient contained in Optimine) has also caused dizziness and affected coordination.

The drowsiness caused by azatadine may subside in some patients following prolonged use. Patients should be warned against driving, as well as concomitant ingestion of alcohol and other sedative-hypnotic drugs, while taking azatadine.

At dosages above what is normally recommended, dystonic reactions have occurred.

Gastrointestinal

Gastrointestinal side effects have included dry mouth and constipation due to anticholinergic effects. Patients have also experienced epigastric distress and nausea. Increased appetite has been reported.

Cardiovascular

Cardiovascular side effects have included hypotension, tachycardia, and palpitations.

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes due to cholinergic blockade.

Genitourinary

Genitourinary side effects have included dysuria, urinary hesitancy, decrease in urinary flow, and in rare cases, acute urinary retention. These urinary tract effects may have been due to azatadine (the active ingredient contained in Optimine) s anticholinergic effects.

Hematologic

Hematologic side effects have included reports of bone marrow suppression, thrombocytopenia, and aplastic anemia.

Respiratory

Respiratory side effects have included thickening of bronchial secretions.

Hypersensitivity

Hypersensitivity reactions to azatadine (the active ingredient contained in Optimine) have included rash and urticaria.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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