Nucynta Side Effects
Generic Name: tapentadol
Note: This page contains side effects data for the generic drug tapentadol. It is possible that some of the dosage forms included below may not apply to the brand name Nucynta.
It is possible that some side effects of Nucynta may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to tapentadol: oral solution, oral tablet, oral tablet extended release
Along with its needed effects, tapentadol (the active ingredient contained in Nucynta) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tapentadol:Less common
- Bladder pain
- bloody or cloudy urine
- body aches or pain
- chills, fever
- difficult, burning, or painful urination
- difficulty with breathing
- loss of voice
- lower back or side pain
- muscle aches
- unusual tiredness or weakness
- Anxiety or nervousness
- being forgetful or confused
- clumsiness or unsteadiness
- fast or irregular heartbeat
- feeling drunk
- irritability or restlessness
- joint pain, stiffness, or swelling
- pale or blue lips, fingernails, or skin
- rash or hives
- sensation of heaviness
- shakiness or trembling
- slurred speech
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- trouble with speaking or hoarseness
- troubled breathing or swallowing
- Changes in behavior
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- seeing, hearing, or feeling things that are not there
- thoughts of killing oneself
Some side effects of tapentadol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Abnormal dreams
- decreased appetite
- difficulty with moving
- heartburn or indigestion
- increased sweating
- muscle pain or stiffness
- redness of the face, neck, arms, and occasionally, upper chest
- stomach discomfort, upset, or pain
- unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
- Change in vision
For Healthcare Professionals
Applies to tapentadol: oral tablet, oral tablet extended release
Gastrointestinal side effects have included nausea, vomiting, constipation, dry mouth, dyspepsia, abdominal discomfort, impaired gastric emptying, and decreased appetite.
Nervous system side effects have included dizziness, somnolence, tremor, lethargy hypoesthesia, paresthesia, disturbance in attention, sedation, dysarthria, depressed level of consciousness, memory impairment, ataxia, presyncope, syncope, abnormal coordination, and seizures. Postmarketing reports have included headache.
Psychiatric side effects have included insomnia, confusional state, abnormal dreams, anxiety, irritability, drug withdrawal syndrome, feeling drunk, euphoric mood, disorientation, restlessness, agitation, nervousness, and abnormal thinking. Postmarketing reports have included hallucinations and panic attacks.
Musculoskeletal side effects have included arthralgia, involuntary muscle contractions, and sensation of heaviness.
Dermatologic side effects have included pruritus, hyperhidrosis, generalized pruritus, and urticaria.
Cardiovascular side effects have included hot flushes, heart rate increased, heart rate decreased, edema, and decreased blood pressure.
Respiratory side effects have included decreased oxygen saturation, cough, dyspnea, upper respiratory tract infection, nasopharyngitis, and respiratory depression.
Genitourinary side effects have included urinary tract infection, urinary hesitation, and pollakiuria.
General side effects have included fatigue and feeling hot.
Immunologic side effects have included hypersensitivity.
Ocular side effects have included visual disturbance.
Postmarketing reports: Anaphylactic shock
More about Nucynta (tapentadol)
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