Nesiritide Side Effects

Medically reviewed by Drugs.com. Last updated on Oct 22, 2023.

Applies to nesiritide: intravenous powder for injection.

Important warnings This medicine can cause some serious health issues

You should not use this medicine if you have very low blood pressure, or if your heart cannot pump blood properly.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have:

• a light-headed feeling, like you might pass out; or

• little or no urination.

Common side effects may include:

• dizziness;

• nausea;

• headache; or

• back pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to nesiritide: intravenous powder for injection.

General

The most frequently reported side effects were hypotension, headache, nausea, renal impairment, and back pain.^[Ref]

Cardiovascular

• Very common (10% or more): Hypotension (12%)^[Ref]

Renal

• Very common (10% or more): GFR decreased (up to 31.4%), serum creatinine increased (up to 28%)^[Ref]

Nervous system

• Common (1% to 10%): Headache, dizziness^[Ref]

Dermatologic

• Postmarketing reports: Pruritus, rash^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain^[Ref]

Metabolic

• Common (1% to 10%): Hypoglycemia^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea^[Ref]

Local

• Postmarketing reports: Infusion site extravasation^[Ref]

Hypersensitivity

• Postmarketing reports: Hypersensitivity reaction^[Ref]

Further information

Nesiritide side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer