Nesiritide Dosage
This dosage information may not include all the information needed to use Nesiritide safely and effectively. See additional information for Nesiritide.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Congestive Heart Failure
Bolus: 2 mcg/kg infused over 60 seconds
Continuous Infusion: 0.01 mcg/kg/min
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Data not available
Dose Adjustments
If hypotension occurs during administration, the dose should be reduced or discontinued and other measures to support blood pressure instituted (IV fluid, body position). A dose reduction of 30% (without a bolus) is recommended in patients after restablizing from symptomatic hypotension.
Precautions
Not for use in patients with cardiogenic shock or with a systolic blood pressure less than 90 mm Hg. Avoid in patients with low cardiac filling pressures.
Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).
Dialysis
Data not available
Other Comments
There is limited experience with administering nesiritide longer than 48 hours. Blood pressure should be monitored closely during administration.
