Almotriptan Side Effects

Brand Names: Axert

Please note - some side effects for Almotriptan may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Almotriptan - for the Consumer

Almotriptan

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Almotriptan:

Dizziness; drowsiness; dry mouth; headache; nausea; sleepiness; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; changes in vision; chest pain; cold, pale, or blue-colored fingers or toes; confusion; fainting; fast or irregular heartbeat; numbness and tingling of hands or feet; one-sided weakness; seizures; severe headache, dizziness, or vomiting; severe stomach pain; shortness of breath; slurred speech; tightness, pain, or pressure in the jaw, neck, or chest; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

Cardiovascular

In one study (n=20), significant effects were reported for the maximal change in diastolic blood pressure and for the maximal and mean change in systolic blood pressure.

Cardiovascular side effects, some fatal, have occurred following the use of 5-HT1 agonists. These events are extremely rare and most have been reported in patients with risk factors predictive of CAD. Such effects include coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia, and ventricular fibrillation. Less frequently reported cardiovascular side effects have included vasodilation, palpitations, and tachycardia. Hypertension and syncope have been rarely reported.

General

General side effects have included headache, abdominal pain or cramp, asthenia, chills, back pain, chest pain, neck pain, fatigue, and rigid neck. Fever and photosensitivity reaction have been rarely reported. Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw have been reported after treatment with almotriptan. (These events were not associated with arrhythmias or ischemic ECG changes in clinical trials.)

Gastrointestinal

Gastrointestinal side effects including nausea and dry mouth have been frequently reported. Less frequently reported gastrointestinal side effects have included diarrhea, vomiting, and dyspepsia. Colitis, gastritis, gastroenteritis, esophageal reflux, increased thirst, and increased salivation have been rarely reported.

Metabolic

Metabolic side effects reported infrequently have included hyperglycemia and increased serum creatine phosphokinase. Increased gamma glutamyltransferase and hypercholesterolemia have been rarely reported.

Musculoskeletal

Musculoskeletal side effects have included myalgia and muscular weakness. Arthralgia, arthritis, and myopathy have been rarely reported.

Nervous system

Nervous system side effects frequently reported have included paraesthesia, dizziness, and somnolence. Less frequently reported nervous system side effects have included tremor, vertigo, anxiety, hyperesthesia, restlessness, CNS stimulation, insomnia, and shakiness. Altered dreams, impaired concentration, abnormal coordination, depressive symptoms, euphoria, hyperreflexia, hypertonia, nervousness, neuropathy, nightmares, and nystagmus have been rarely reported.

Respiratory

Respiratory side effects including pharyngitis, rhinitis, dyspnea, laryngismus, sinusitis, bronchitis, and epistaxis have been reported infrequently. Hyperventilation, laryngitis, and sneezing have been reported rarely.

Dermatologic

Dermatologic side effects including diaphoresis, dermatitis, erythema, pruritus, and rash have been infrequently reported.

Other

Special sense reactions have included ear pain, conjunctivitis, eye irritation, hyperacusis, and taste alteration. Diplopia, dry eyes, eye pain, otitis media, parosmia, scotoma, and tinnitus have been rarely reported.

Genitourinary

Genitourinary side effects reported infrequently have included dysmenorrhea.

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