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User Reviews for Methotrexate

Also known as: Folex PFS, Methotrexate LPF Sodium, Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Methotrexate.

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Summary of Methotrexate reviews 69 reviews 8.0

Reviews for Methotrexate

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Review by ACS3:

User Rating:  
   
6.0

For Rheumatoid Arthritis: I have been on methotrexate for almost a year. I am up to 20 mg a week. I take folic acid and leucovorin calcium 12 hours after the methotrexate. I was taking Enbrel but now take Xeljanz. Before the biologics the methotrexate wasn't working very well. I take prednisone too. I am only 36 but at least I can function better than I did. I still flare about twice a month. I suffer side effects from methotrexate. My hair has severely thinned out and I get very tired after taking it. It looks like I'll be on it for a long time tho. Hopefully it gets better. I would really Like my hair to come back.

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July 5, 2014 9:42 PM

Review by Dpalmer63 (taken for 1 to 6 months):

User Rating:  
   
10

For Rheumatoid Arthritis: I have been on methotrexate for two months now and have slowly increased my dose to 17.5mg/week. I started on a daily dose of folic acid but switched to a weekly dose of Leucovorin due to dizziness a couple of days after my Methotrexate dose. My pain and inflammation are gone and I feel so much better. I am once again able to do the things I love and have no side effects. I'm RF negative, but my rheumatologist chose to treat me quickly and aggressively based on symptoms and a high CCP. I'm thankful she did. I hope Methotrexate will be a long term solution to treat my rheumatoid arthritis.

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July 1, 2014 3:58 PM

Review by Mrs DT (taken for 1 to 6 months):

User Rating:  
   
9.0

For Psoriasis: I have suffered with psoriasis since I was 19years old now in my 40s I have tried everything on the market, been on methotrexate since New Year's Day and I am so happy to say that it has nearly all gone. I holiday with all my friends and don't feel embarrassed, I am so happy. I would recommend, it's a slow process but five months in and pretty much clear. No side effects, tired on day of medication but that's no issue.

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June 9, 2014 5:02 PM

Review by LeopardHat (taken for 6 months to 1 year):

User Rating:  
   
9.0

For Psoriasis: I live in the UK & have had plaque psoriasis for 20 yrs. After various lotions, UVB & PUVA, my knees & elbows became infected and I could hardly walk or sleep with the discomfort. As I also have depression, my dermatologist decided on prescribing methotrexate as my quality of life was so severely affected. I take 15mg tablets once a week, within a month it had all but gone, & has remained that way. It has been a year since I started, it's such a relief not to think about my knees all the time! I also take folic acid, & the skin on my face has become quite oily, but it's definitely worth it. I've recently noticed the few patches I have left are beginning to increase in size, but I hope this improves with the arrival of summer!

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May 6, 2014 5:54 PM

Review by kpalchk (taken for 1 to 2 years):

User Rating:  
   
6.0

For Rheumatoid Arthritis: I've had rheumatoid arthritis (RA) for 35 years. I finally found a rheumatologist that was very good. I started on Plaquenil, which was great, but I developed an allergy to it. Switched to methotrexate oral, but had a hard time tolerating the nausea and diarrhea. Switched to injectable methotrexate, and had no nausea, limited diarrhea. It worked moderately well for the RA. Not completely pain free, but could do most things most days. I got cellulitis while on it, so had to go off for about 3 mos. When I went back to it, it didn't seem to work quite as well, and I realized I was experiencing more side effects than I was aware of the first time: thin skin, dermatitis, bruising, bleeding, hair falling out. New rheumatologist (my good one moved) decided to try Arava.

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January 9, 2014 9:12 PM

Review by Kimmy9519:

User Rating:  
   
10

For Psoriasis: Tried all other methods for relief of psoriasis, 80% of body. Have been on methotrexate for 5.5 weeks, belly, back, chest and forearms are all clear, very mild psoriasis that isn't red or irritated on upper arms and lower legs. My confidence and self esteem has increased heaps, excited to go for a swim 2nd time since I've had psoriasis (7 years). Only had bad fatigue for first few weeks, haven't drank any alcohol, healthy diet with minimal junk food, and nausea if I eat something really, fatty eg. pizza. Skin colour isn't yellowing nor getting black under the eyes, or anything else relating to bad liver. Would definitely recommend this medication.

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January 6, 2014 6:41 PM

Review by scaly girl (taken for less than 1 month):

For Psoriasis: I have had psoriasis on my scalp since I was a baby with "Cradle Cap.'' It was left untreated until I was about 21. I have tried every cream and t-gel out there. Nothing cleared it up fully. Since I turned 24 the condition has spread to other parts of my body, usually parts that don%u2019t get much light. Psoriasis is terrible and affects everyone so differently. This condition has kept me from getting close to people and even kept me from going to hair dressers. Finally I decided to start this medicine. I'm currently on my fourth week of 15mg oral methotrexate. I have noticed a huge decrease in itching and my patches seem to be not as scaly. I really hope this works, so far so good.

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December 30, 2013 11:29 AM

Review by Kimber321 (taken for 1 to 2 years):

User Rating:  
   
7.0

For Psoriasis: This drug greatly helped my psoriatic arthritis, but not the plaque poriasis, which always came back. I've been through the scrip topicals, light treatments, Amiveve, etc. I was 98% covered. Why did not a single doctor ever tell me NOT to touch beer???? If you drink beer put it DOWN and see how quickly you begin to clear up. Pork is another culprit as it is slow to digest and effects the immune system. For topical relief? Try OTC Boudreaux's Butt Paste baby diaper rash cream, which far outshines Dovonex. Scalp treatment? Nutrogena T-Gel Shampoo works quickly. If you are severely covered add zinc or zinc supplements to your diet. I haven't gone to a derm in years and I am clear!!!!

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November 4, 2013 3:48 PM

Review by Anonymous (taken for 1 to 6 months):

User Rating:  
   
8.0

For Psoriasis: I have had psoriasis since I can remember, last year after a foot injury I developed psoriatic arthritis. Since it has spread to both feet, both knees, one hand and lower back. Leaving me hardly being able to walk at 30. I started methotrexate 4 weeks ago and it is helping a lot. Only side effects for me are fatigue. I do 1 ml injections once a week. If you have PsA, get on methotrexate. If you can handle the needles injections are the way to go.

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October 26, 2013 8:50 AM

Review by MoneyMan (taken for 6 months to 1 year):

User Rating:  
   
10

For Psoriatic Arthritis: I have been using 20 mg for over a year with few side effects. It didn't take away pain and stiffness 100%, so my doctor included Humira. With both meds I am virtually pain free, stiffness and inflamation gone. Before I began treatment, I couldn't tie my shoes, write a letter, or open a jar. Now all of those activities are effortless.

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September 22, 2013 7:21 PM

Review by Arouran Moon (taken for less than 1 month):

User Rating:  
   
10

For Psoriasis: Started taking methotrexate approx. 1 and a 1/2 weeks ago. Already have seen significant improvements. I have had over 75% coverage of psoriasis from head to toe since my teens and I am now 45. Minor troubling side effect include slight nausea, bad fatigue and dizziness. These clear up after I finish my three day treatment. Positive outweighs the negative. I am scheduled for my first liver test on Oct 1st. In my opinion ...worth it!

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September 13, 2013 8:33 PM

Review by stargirl589:

User Rating:  
   
10

For Psoriasis: During the Christchurch earthquakes my mother (who's had psoriasis all her life) and myself broke out big time. We found a specialist and got put on this. It cleared up in a matter on 2 weeks for mum, for me it was 3-4 weeks. We both have had no side effects. However, now 1 yr later after moving to Auckland I can't find a doctor who will supply it to me. One week from being off it and has all come back. Just want to be a normal 20 yr old. If you got a doctor who prescribes this, don't let them go.

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July 29, 2013 6:40 AM

Review by laurenban:

User Rating:  
   
8.0

For Psoriasis: I am just diagnosed with psoriasis on May 2013 and I am on my 3rd week of methotrexate and so far it cleared the psoriasis on my neck and under my breast. It stops the wetness and flakes and the ones in my arm and tummy are lesser in flakes. I just hope that my dermatologist will allow me to continue the medicine, but it depends on the lab results on my liver.

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July 22, 2013 1:18 AM

Review by ARn26 (taken for 1 to 6 months):

User Rating:  
   
7.0

For Psoriasis: I have been suffering with psoriasis for 4 years now and with each year it keeps on getting worse. The guttate psoriasis covers 80% of my body. I have tried ointments, light therapy and now methotrexate. All treatments work for a while but oddly enough the psoriasis comes back with vengeance. New spots appear. My dermatologist explained to me that it takes 3 months for methotrexate to work. It slightly cleared up my Psoriasis the first month but on the third month my psoriasis came back even worse. I'm glad to read that this medicine has done wonders for many but it just didn't work for me.

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July 5, 2013 3:41 PM

Review by Nakuru5:

User Rating:  
   
8.0

For Rheumatoid Arthritis: I have taken methotrexate for 17 years and am now on 20mg per week. I have also been on Rituximab infusions for the past 3 years and together the two medicines work very well. I am mostly pain free, except for mornings.

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July 1, 2013 4:36 PM

Review by azure71:

User Rating:  
   
3.0

For Psoriasis: Just started a week ago. Was nervous regarding side effects but bit the nerves. Notice there is no flaking after one week. Although still itchy hopefully that goes away. Just felt like I was exhausted faster but want to keep giving it a try. Tried everything else.

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June 6, 2013 12:33 AM

Review by Karinttt (taken for 2 to 5 years):

User Rating:  
   
9.0

For Psoriatic Arthritis: I've been on methotrexate for 3 years at 8 tablets (2.5 mgs). For some reason I only have psoriasis on my hands and then only my thumbs and the center of my inside right hand. That has cleared up considerably to where it is no problem. Thank goodness I have not got it anywhere else. I noticed that my knees, which had been painful, stopped hurting entirely after about six months. Before it was quite painful... now I have no pain. I haven't been taking the folic acid like I should.

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April 9, 2013 11:30 AM

Review by fluffynut (taken for 6 months to 1 year):

User Rating:  
   
9.0

For Psoriasis: I've had severe psoriasis which covered me head to toe since I was 5 I'm now 30. Tried every trick in the book from lotions and potions, light therapy & homeopathic remedies. I put off taking methotrexate for fear of becoming a glow in the dark alien with the side effects! Finally gave in last year and so glad I did. It cleared within 3 weeks. I'm now on 15mg a week and only have slight patches of psoriasis dotted about. Had a few bad headaches now and then but nothing extreme. A little wobbly on the blood tests but nothing life threatening just yet. Much better quality of life at the min, and much less hoovering haha.

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April 5, 2013 11:31 AM

Review by oneta:

User Rating:  
   
10

For Psoriasis: My mother broke out seemed like overnight with red bumps that quickly turned into dry patches. The dermatologist knew right away what it was. We have been on the Methotrexate for 6 weeks and the flaking is totally gone and is healing. The dose was 2 Friday morning, 2 Friday evening and 2 Saturday morning. Only side effect was appetite and very tired for 2 days.

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March 30, 2013 6:22 PM

Review by george b:

User Rating:  
   
8.0

For Eczema: After suffering from about 5 years old, I'm now 56. Only been on the medication for approx 9 weeks the improvement has been amazing. I've been unable to cope with the pain and spent many days in bed over the years so touch wood this medication will keep on working.

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February 22, 2013 8:38 AM

Review by Pipeline girl:

User Rating:  
   
10

For Psoriasis: I have been on methotrexate for 2 1/2 years, I cleared up within 2 months and have stayed cleared up! Knowing you can only have so many grams in a certain amount of time makes me sad because soon I will have to stop taking it and switch to something different. I am 39 and have had psoriasis since I was 21. I can wear shorts and a t-shirt and feel normal. Methotrexate has given me my freedom back and I have had no side effects. If you have psoriasis you should give it a try, for me it's been so worth it.

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January 16, 2013 6:53 PM

Review by Big Momma 2012 (taken for 1 to 6 months):

User Rating:  
   
8.0

For Rheumatoid Arthritis: After many years of joint pain, finally found a physician who looked at x-rays, labs, family history, my entire medical history and determined that I indeed had Rheumatiod Arthritis. I have noticed a significant change after being put on Methotrexate, Prednisone, Folic Acid, and Tramadol. However, now that winter is here, joints are worse and I am now on the highest dose of Methotrexate (20mg) a week but I'm able to get out and do more with less pain than before.

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November 7, 2012 3:21 PM

Review by Anonymous:

User Rating:  
   
2.0

Rheumatrex Dose Pack (methotrexate) for Rheumatoid Arthritis: Took methotrexate for 6 months after diagnosis for Rheumatoid arthritis, seemed to work fairly well for the pain/stiffness, but I had terrible side effects including nausea, fatigue, mood swings - almost couldn't get to work, coming up stairs felt like my feet weighed 500 pounds each - almost could not function at all. Now going to try in injectable form to see if that will not cause the side effects - hopeful.

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October 19, 2012 1:50 PM

Review by Anonymous:

User Rating:  
   
10

For Rheumatoid Arthritis: I am female, 41, have been taking methotrexate for 2 months now. I was crippled, my hands fingers wrists ankles balls of my feet knees shoulders arms even my jaw. I could barely walk I couldn't unscrew lids, peel potatoes, do everyday chores people take for granted. My rheumatoid factor was 1380. After 1 month no change hopefully my 2nd reading it will come down. Anyway after 1 month on the medication my joint pains has disappeared thanks to Methotrexate. I take 10mg once weekly with folic acid next day. Worked for me. YAY!

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September 23, 2012 12:06 PM

Review by Uk lady (taken for 1 to 6 months):

User Rating:  
   
8.0

For Rheumatoid Arthritis: I have only been taking this medicine for a short while and the benefits are good so far. I am still able to keep working as a Paramedic which is physically demanding. Without my 20mg I slowly turn into a statue.

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August 15, 2012 7:43 PM

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