Also known as: Folex PFS, Methotrexate LPF Sodium, Otrexup, Rheumatrex Dose Pack, Trexall
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Reviews for Methotrexate to treat Rheumatoid Arthritis
Review by kpalchk (taken for 1 to 2 years):
methotrexate: I've had rheumatoid arthritis (RA) for 35 years. I finally found a rheumatologist that was very good. I started on Plaquenil, which was great, but I developed an allergy to it. Switched to methotrexate oral, but had a hard time tolerating the nausea and diarrhea. Switched to injectable methotrexate, and had no nausea, limited diarrhea. It worked moderately well for the RA. Not completely pain free, but could do most things most days. I got cellulitis while on it, so had to go off for about 3 mos. When I went back to it, it didn't seem to work quite as well, and I realized I was experiencing more side effects than I was aware of the first time: thin skin, dermatitis, bruising, bleeding, hair falling out. New rheumatologist (my good one moved) decided to try Arava.
methotrexate: I have taken methotrexate for 17 years and am now on 20mg per week. I have also been on Rituximab infusions for the past 3 years and together the two medicines work very well. I am mostly pain free, except for mornings.
26 users found this comment helpful.
Review by Big Momma 2012 (taken for 1 to 6 months):
methotrexate: After many years of joint pain, finally found a physician who looked at x-rays, labs, family history, my entire medical history and determined that I indeed had Rheumatiod Arthritis. I have noticed a significant change after being put on Methotrexate, Prednisone, Folic Acid, and Tramadol. However, now that winter is here, joints are worse and I am now on the highest dose of Methotrexate (20mg) a week but I'm able to get out and do more with less pain than before.
47 users found this comment helpful.
Rheumatrex Dose Pack (methotrexate): Took methotrexate for 6 months after diagnosis for Rheumatoid arthritis, seemed to work fairly well for the pain/stiffness, but I had terrible side effects including nausea, fatigue, mood swings - almost couldn't get to work, coming up stairs felt like my feet weighed 500 pounds each - almost could not function at all. Now going to try in injectable form to see if that will not cause the side effects - hopeful.
42 users found this comment helpful.
methotrexate: I am female, 41, have been taking methotrexate for 2 months now. I was crippled, my hands fingers wrists ankles balls of my feet knees shoulders arms even my jaw. I could barely walk I couldn't unscrew lids, peel potatoes, do everyday chores people take for granted. My rheumatoid factor was 1380. After 1 month no change hopefully my 2nd reading it will come down. Anyway after 1 month on the medication my joint pains has disappeared thanks to Methotrexate. I take 10mg once weekly with folic acid next day. Worked for me. YAY!
44 users found this comment helpful.
methotrexate: I have only been taking this medicine for a short while and the benefits are good so far. I am still able to keep working as a Paramedic which is physically demanding. Without my 20mg I slowly turn into a statue.
29 users found this comment helpful.
methotrexate: I have been taking the medication sine June 2011 I like it, but I'm always sick. It minimizes the pain and swelling, but it doesn't take it all away. I wake up every morning, and I can hardly move my ankles. I'm way to young to have to deal with this I'm only 22 years old. Some days I feel like I'm suffering, and if I'm sick I can't even walk.
33 users found this comment helpful.
methotrexate: Started taking methotrexate 24th November 4 x 2.5mg weekly. Didn't feel to bad until Sat 3rd December and felt really ill. I had the flu jab as well hopefully things will improve but I was in bed from Saturday until today and I have a taste of metal in my mouth, I can't eat and haven't enjoyed a cup of tea. I also take the folic acid. I have lost 4lb in weight since Saturday.
31 users found this comment helpful.
methotrexate: I have been taking this medicine since June and recently increased my dose. This medication has not worked for me at all. I continue to have pain and swelling in my wrist and fingers. The only thing that works for me is prednisone.
35 users found this comment helpful.
methotrexate: I'm 30 years old and have been on 20mg of methotrexate for 2 years now. While I have experienced some side effects (mainly abdominal pain) I would not and will not stop taking it. So far for me the benefits have far outweighed any costs of being on methotrexate. The disease activity has dropped and I have far less swelling in my wrists, fingers and shoulders and have been able to get back into bowling leagues which I love.
47 users found this comment helpful.
methotrexate: Taking 12.5mg/week along with Prilosec due to stomach ulcers from too many NSAIDS. Works well on the rheumatoid arthritis symptoms. Have been bumping the dose up from 7.5 mg/week and have now run into low platelet count 85 when it should run between 150 and 400. I'm backing off of the methotrexate to see if I get a recovery of my platelet levels. Did a two month stint without methotrexate and was in massive pain (all the Vicodin in the world could not touch it). It works but hopefully I'll be able to get by on the lower dose and get a comeback in platelet levels.
51 users found this comment helpful.
methotrexate: This medicine is wonderful. Without it I could not move my fingers and wrists and my knees and ankles. I feel normal and people cannot believe that I have RA. The only down side is my skin on my arms is thinned and very easy to bruise and bleed and marks but as this is a small price to pay for a normal lifestyle and to be able to work.
69 users found this comment helpful.
methotrexate: It definitely helps with the pain and mobility part of rheumatoid arthritis, but I am nauseous usually 2 or three days after I do the shot. I'm also tired a lot and feel weak after I take my weekly shot. Sometimes I don't take it consistently because I don't feel like being sick that week. I do enjoy it when my fingers actually bend though.
69 users found this comment helpful.
methotrexate: I have been taking methotrexate for about 2 years for moderate rheumatoid arthritis (22.5mg weekly) and it does control inflammation. I recently stopped taking it for 3 months because I really don't like taking drugs and symptoms returned (inflammation in ankles, hip pain, stiffness) so I started taking it again and have no pain so obviously it was working.
124 users found this comment helpful.
methotrexate: At first I was really apprehensive about taking Methotrexate (7.5mg a week), but it seems to be working well. I've been taking it since November 2008. My side effects are minimal. Once a week I get nausea, which usually occurs the day after I take my weekly dose. My tests results have come back normal too. I 'm not a medicine taker and the idea of taking such a strong medication still scares me, but I will continue with my weekly dosage because it helps with my rheumatoid arthritis a lot. One thing I'm consistent with is taking my Folic Acid since it helps prevent my side effects. I don't even get the very common mouth sores.
190 users found this comment helpful.
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