Also known as: Folex PFS, Methotrexate LPF Sodium, Otrexup, Rheumatrex Dose Pack, Trexall
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Compare all 234 medications used in the treatment of Psoriasis.
Reviews for Methotrexate to treat Psoriasis
Review by Kimber321 (taken for 1 to 2 years):
methotrexate: This drug greatly helped my psoriatic arthritis, but not the plaque poriasis, which always came back. I've been through the scrip topicals, light treatments, Amiveve, etc. I was 98% covered. Why did not a single doctor ever tell me NOT to touch beer???? If you drink beer put it DOWN and see how quickly you begin to clear up. Pork is another culprit as it is slow to digest and effects the immune system. For topical relief? Try OTC Boudreaux's Butt Paste baby diaper rash cream, which far outshines Dovonex. Scalp treatment? Nutrogena T-Gel Shampoo works quickly. If you are severely covered add zinc or zinc supplements to your diet. I haven't gone to a derm in years and I am clear!!!!
methotrexate: I have had psoriasis since I can remember, last year after a foot injury I developed psoriatic arthritis. Since it has spread to both feet, both knees, one hand and lower back. Leaving me hardly being able to walk at 30. I started methotrexate 4 weeks ago and it is helping a lot. Only side effects for me are fatigue.
I do 1 ml injections once a week. If you have PsA, get on methotrexate. If you can handle the needles injections are the way to go.
Review by Arouran Moon (taken for less than 1 month):
methotrexate: Started taking methotrexate approx. 1 and a 1/2 weeks ago. Already have seen significant improvements. I have had over 75% coverage of psoriasis from head to toe since my teens and I am now 45. Minor troubling side effect include slight nausea, bad fatigue and dizziness. These clear up after I finish my three day treatment. Positive outweighs the negative. I am scheduled for my first liver test on Oct 1st. In my opinion ...worth it!
10 users found this comment helpful.
methotrexate: During the Christchurch earthquakes my mother (who's had psoriasis all her life) and myself broke out big time. We found a specialist and got put on this. It cleared up in a matter on 2 weeks for mum, for me it was 3-4 weeks. We both have had no side effects. However, now 1 yr later after moving to Auckland I can't find a doctor who will supply it to me. One week from being off it and has all come back. Just want to be a normal 20 yr old. If you got a doctor who prescribes this, don't let them go.
methotrexate: I am just diagnosed with psoriasis on May 2013 and I am on my 3rd week of methotrexate and so far it cleared the psoriasis on my neck and under my breast. It stops the wetness and flakes and the ones in my arm and tummy are lesser in flakes. I just hope that my dermatologist will allow me to continue the medicine, but it depends on the lab results on my liver.
11 users found this comment helpful.
methotrexate: I have been suffering with psoriasis for 4 years now and with each year it keeps on getting worse. The guttate psoriasis covers 80% of my body. I have tried ointments, light therapy and now methotrexate. All treatments work for a while but oddly enough the psoriasis comes back with vengeance. New spots appear. My dermatologist explained to me that it takes 3 months for methotrexate to work. It slightly cleared up my Psoriasis the first month but on the third month my psoriasis came back even worse. I'm glad to read that this medicine has done wonders for many but it just didn't work for me.
13 users found this comment helpful.
methotrexate: Just started a week ago. Was nervous regarding side effects but bit the nerves. Notice there is no flaking after one week. Although still itchy hopefully that goes away. Just felt like I was exhausted faster but want to keep giving it a try. Tried everything else.
Review by fluffynut (taken for 6 months to 1 year):
methotrexate: I've had severe psoriasis which covered me head to toe since I was 5 I'm now 30. Tried every trick in the book from lotions and potions, light therapy & homeopathic remedies. I put off taking methotrexate for fear of becoming a glow in the dark alien with the side effects! Finally gave in last year and so glad I did. It cleared within 3 weeks. I'm now on 15mg a week and only have slight patches of psoriasis dotted about. Had a few bad headaches now and then but nothing extreme. A little wobbly on the blood tests but nothing life threatening just yet. Much better quality of life at the min, and much less hoovering haha.
34 users found this comment helpful.
methotrexate: My mother broke out seemed like overnight with red bumps that quickly turned into dry patches. The dermatologist knew right away what it was. We have been on the Methotrexate for 6 weeks and the flaking is totally gone and is healing. The dose was 2 Friday morning, 2 Friday evening and 2 Saturday morning. Only side effect was appetite and very tired for 2 days.
20 users found this comment helpful.
methotrexate: I have been on methotrexate for 2 1/2 years, I cleared up within 2 months and have stayed cleared up! Knowing you can only have so many grams in a certain amount of time makes me sad because soon I will have to stop taking it and switch to something different. I am 39 and have had psoriasis since I was 21. I can wear shorts and a t-shirt and feel normal. Methotrexate has given me my freedom back and I have had no side effects. If you have psoriasis you should give it a try, for me it's been so worth it.
48 users found this comment helpful.
Review by Anonymous (taken for 6 months to 1 year):
methotrexate: It works great! I have had Psoriasis all my adult life and only two things have worked. The first was the original Skin Cap spray from Spain but that disappeared after the U.S. government got involved. This was second. I have been on methrotrexate 2.5mg tablets for 6 months and was fully clear within the first month. No stomach problems and no other side effects. If you suffer from psoriasis, do yourself a favor and find a doctor that will work with you to try it.
34 users found this comment helpful.
methotrexate: I have been on 15mg methotrexate for one year for psoriasis and psoriatic arthritis. My psoriasis was mild to moderate and is a little better but I was in a lot of pain from the arthritis and this medicine has helped me so much. I would say my pain went from a 9 to a 3 on a scale of 1- 10. Only side effect is stomach upset and I am considering switching to injections.
27 users found this comment helpful.
methotrexate: I have had psorisis all my life (45 yrs). I have been a methotrexate user for 12 years. Before I started using methotrexate I was covered about 90%. Today it is about 1%. Over the years along with blood work. I have had 3 liver biopsy. I have had no side effect.
44 users found this comment helpful.
methotrexate: I have had psoriasis for over 40 years, and although it's just on my elbows and legs, I have tried all the usual remedies (topicals, light therapy, etc.). I tried methotrexate this spring and in a matter of weeks, my psoriasis began to clear up. My doctor has me go for blood-work every month or so to make sure the methotrexate isn't affecting my liver. We have decided to back off of the methotrexate during the winter in order to give my body a break. But, I'll be anxious to begin it again come spring!
33 users found this comment helpful.
methotrexate: I have been in methotrexate for 6 weeks now. So far, itchiness has been reduced significantly; lesions in my lower leg have dried up (light brown now); other lesions appear to be clearing up though slowly. Side effects to me are nausea, feeling giddy and occasional headache though not severe.
May I ask those who are in the same medication: how long did it take for all lesions to be cleared? about 70% of my body has psoriasis. Thank you. .
19 users found this comment helpful.
methotrexate: I have had severe psoriasis on my hands, elbows, and heels for the past 2 years. Came out of nowhere. Tried everything out there (steroids, antihistamines, light treatments (two periods of it)
So now I'm on this medicine. It's only for the second week, but the only difference I see is getting a urinary tract infection. Hopefully I will see improvement soon.
methotrexate: I have had psoriatic arthritis since age 10. The deformities in my hands are very, very severe. I have taken methotrexate for about 6 weeks, and don't notice a difference, except have been feeling sick to my stomach, tired, and bowel - movements are painful and a little blood is visible. Kinda scary--I see my rhematologist in a few weeks. Psoriasis patches seem burning or itchier.
12 users found this comment helpful.
methotrexate: I have had psoriasis for over 10 years and for the first 5 years it was very mild, but in 2005 it quickly got worse and covered 70% of my body in various spots such as my entire scalp, under my breasts, on my elbows and knees, in my pelvic area and a few other random spots. I was prescribed (5) 25mg pills (1x wk) of methotrexate after trying every cream imaginable and the photo light therapy. The medication made me extremely sick to my stomach. After seeing some improvement my dermatologist recommended I try the tanning bed along with the medication. Within 6 months my psoriasis was completely gone. 4 years after being off the medicines it has come back. It is worse than before and I am taking the medicines and am getting sick a lot. Hope it works again.
28 users found this comment helpful.
methotrexate: I have suffered several types of chronic psoriasis, including the life threatening form for 50 years. After developing severe disability from Psoriatic Arthritis I gave in to taking this drug, my skin is 90% improved, inflammation much better, but still have high inflammatory markers in blood tests. Now on steroids. Nausea still persists so I take folic acid.
32 users found this comment helpful.
methotrexate: I have been a victim of psoriasis for the last seven years. I came to know about this drug from a skin specialist in the year 2004. Prior to this I was covered up to 75% but when I took this it vanished after taking a mere 30 mg. It recurred in year 2005. Since then I am taking it frequently, as I did not find any other alternative to fight this skin disorder. As far as my personal experience is concerned, I didn't have any side effect.
48 users found this comment helpful.
methotrexate: I have been on methotrexate now for 6 months. Its great as I was 85% covered with psoriasis and it improved almost instantly by 90%. Although there is one drawback, I get recurrent bouts of bacterial vaginosis, which is most uncomfortable and have to then take high dose of antibiotics (which make me feel very sick for a few days).
33 users found this comment helpful.
methotrexate: I've been on this medicine for about 3 weeks. I have psoriasis on my hands and feet. I can walk again and do NORMAL things without my hands cracking and bleeding. So far I haven't had any side effects that are related to this medication.
47 users found this comment helpful.
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