Tiotropium
Generic Name: Tiotropium (TYE-oh-TROE-pee-um)
Brand Name: Spiriva HandiHaler
Tiotropium is used for:
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Treating symptoms of chronic obstructive pulmonary disease (COPD), including bronchitis and emphysema. It may also be used for other conditions as determined by your doctor.
Tiotropium is an anticholinergic agent. It works by enlarging the airways to allow easier breathing.
Do NOT use Tiotropium if:
- you are allergic to any ingredient in Tiotropium or to atropine or related medicines (eg, ipratropium)
- you are taking another anticholinergic (eg, ipratropium)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Tiotropium :
Some medical conditions may interact with Tiotropium . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have difficulty urinating because of an enlarged prostate or blockage of the bladder neck, or you have glaucoma, or kidney problems
- if you are having an asthma attack or increased difficulty breathing
Some MEDICINES MAY INTERACT with Tiotropium . Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticholinergics (eg, ipratropium) because they may increase the risk of Tiotropium 's side effects. Ask your doctor if you are unsure if any of your medicines are anticholinergics.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Tiotropium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Tiotropium :
Use Tiotropium as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Tiotropium . Talk to your pharmacist if you have questions about this information.
- Do not swallow the capsules. The capsules are used with a special inhaler.
- To remove the capsule from the packaging, peel back the foil and tip the capsule out. Do NOT cut the foil or use anything sharp to remove the capsule.
- Do not remove a capsule from the packaging until you are ready to use it. If a second capsule is exposed to the air when you are removing a capsule for use, it must be discarded. Do not save the capsule for later.
- The capsule must immediately be placed in a special inhaler device. The device will puncture the capsule so that the medicine inside may be inhaled into the lungs through the mouthpiece. Exhale slowly and deeply. Do not exhale into the mouthpiece of the inhaler. Position the inhaler mouthpiece between your lips and try to rest your tongue flat. Keep your head upright. Take a slow, deep breath. You should hear or feel the capsule vibrate inside the inhaler. Hold your breath for as long as it feels comfortable, then exhale slowly through pursed lips. Breathe out completely.
- To be sure all of the medicine has been inhaled from the capsule, inhale from the mouthpiece a second time following the same process.
- Ask your doctor or pharmacist if you are unclear on how to use this device or inhale the medicine. Clean the inhaler device once a month according to the instructions in the patient leaflet.
- Each inhaler device may be used for up to 1 year and then should be replaced.
- Using Tiotropium at the same time each day will help you remember to use it.
- Use Tiotropium on a regular schedule to get the most benefit from it.
- If you miss a dose of Tiotropium , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. Do not use Tiotropium more often than 1 time every 24 hours.
Ask your health care provider any questions you may have about how to use Tiotropium .
Important safety information:
- Tiotropium may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Tiotropium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Tiotropium will not stop an asthma attack once it has started. If you are also using a rescue inhaler (eg, albuterol), be sure to always carry it with you to use during asthma attacks.
- Avoid getting Tiotropium in your eyes. If you get Tiotropium in your eyes and eye pain, blurred vision, or other vision changes occur, contact your doctor immediately.
- Tiotropium may sometimes cause severe breathing problems right after you use a dose. If this happens, use your short-acting bronchodilator inhaler. Contact your doctor or seek other medical care at once.
- Use Tiotropium with caution in the ELDERLY; they may be more sensitive to its effects, especially constipation or urinary tract infections.
- Tiotropium should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tiotropium while you are pregnant. It is not known if Tiotropium is found in breast milk. If you are or will be breast-feeding while you use Tiotropium , check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Tiotropium :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:Blurred vision; constipation; dry mouth; mild nosebleed; sinus inflammation; sore throat; stomach pain; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; difficult or painful urination; eye pain or discomfort; fast or irregular heartbeat; irritation, pain, or white patches in the mouth or on the tongue; mouth sores; new or worsened breathing problems; severe or persistent constipation; severe or persistent nosebleed; trouble swallowing; vision changes; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include mental changes; severe constipation; stomach pain; tremors.
Proper storage of Tiotropium :Store Tiotropium at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tiotropium out of the reach of children and away from pets.
General information:
- If you have any questions about Tiotropium , please talk with your doctor, pharmacist, or other health care provider.
- Tiotropium is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Tiotropium . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
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More Tiotropium resources
tiotropium Inhalation, oral/nebulization - Includes detailed dosage instructions.
Compare Tiotropium with other medications for the treatment of:
Chronic Obstructive Pulmonary Disease, Maintenance
