Generic Name: tiotropium inhalation (tye oh TROE pee um)
Brand Name: Spiriva
What is tiotropium inhalation?
Tiotropium is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs.
Tiotropium inhalation is used to prevent bronchospasm (narrowing of the airways in the lungs) in people with bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).
Tiotropium inhalation may also be used for purposes not listed in this medication guide.
What is the most important information I should know about tiotropium inhalation?
A tiotropium capsule is for use only in the HandiHaler device. Do not take the capsule by mouth. Use only one capsule at a time.
What should I discuss with my healthcare provider before using tiotropium inhalation?
You should not use this medication if you are allergic to tiotropium or ipratropium (Atrovent, Combivent, DuoNeb).
To make sure tiotropium inhalation is safe for you, tell your doctor if you have:
enlarged prostate or urination problems;
if you are allergic to milk; or
if you take Parkinson's disease medication, bladder or urinary medicines, stomach ulcer medicine, or medicines to treat irritable bowel syndrome.
FDA pregnancy category C. It is not known whether tiotropium inhalation is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether tiotropium inhalation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I use tiotropium inhalation?
Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
The tiotropium capsule is for use only in the HandiHaler device. Do not take the capsule by mouth. Use only one capsule at a time.
Tiotropium inhalation will not work fast enough to treat an asthma attack. Use only a fast acting inhalation medicine for an asthma attack. Tell your doctor if it seems like your asthma medications don't work as well.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Use tiotropium inhalation regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
To be sure this medication is helping your condition, your lung function will need to be tested on a regular basis.
Store at room temperature away from moisture and heat. Do not freeze.
Keep each tiotropium capsule in its blister pack until you are ready to place the capsule into the HandiHaler and use the device. Throw away any capsule that is not used right after you have taken it out of the blister pack. Exposure to air can ruin the capsule.
What happens if I miss a dose?
Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.
Do not use the Spiriva HandiHaler more than 1 time in a 24-hour period.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include dry mouth, eye redness, constipation, stomach pain, and confusion or drowsiness.
What should I avoid while using tiotropium inhalation?
Avoid getting the powder from a tiotropium capsule in your eyes. If this does happen, call your doctor.
Avoid taking medicine to prevent motion sickness, cold or allergy medicine that contains an antihistamine, or medication to treat excess stomach acid while you are using tiotropium inhalation. Ask your doctor about the best ways to treat these conditions.
Tiotropium inhalation side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives, itching; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
wheezing, choking, or other breathing problems after using this medication;
blurred vision, eye pain or redness, seeing halos around lights;
sores or white patches of your mouth, lips, or tongue;
pain or burning when you urinate; or
little or no urinating.
Common side effects may include:
cold symptoms such as stuffy nose, runny nose, sore throat;
upset stomach; or
fast heart rate.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Tiotropium inhalation dosing information
Usual Adult Dose for Chronic Obstructive Pulmonary Disease -- Maintenance:
18 mcg by oral inhalation once a day
-One capsule contains 18 mcg of tiotropium (dry powder formulation).
-The full dose is delivered via 2 inhalations from 1 capsule using the HandiHaler(R) device.
Approved indications: For the long-term maintenance therapy of bronchospasm associated with COPD, including chronic bronchitis and emphysema; to reduce exacerbations in COPD patients
What other drugs will affect tiotropium inhalation?
Other drugs may interact with tiotropium inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about tiotropium
- Other brands: Spiriva
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about tiotropium inhalation.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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