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Ticarcillin

Generic Name: ticarcillin (TYE-kar-SIL-in)
Brand Name: Ticar

Ticarcillin is used for:

Treating infections caused by certain bacteria.

Ticarcillin is a penicillin antibiotic. It works by blocking the growth of the bacteria's cell wall, resulting in the death of the bacteria.

Do NOT use ticarcillin if:

  • you are allergic to any ingredient in ticarcillin or to penicillin antibiotics (eg, amoxicillin)
  • you are taking a tetracycline antibiotic (eg, doxycycline)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: The Shocking Truth About Antibiotic Resistance

Before using ticarcillin:

Some medical conditions may interact with ticarcillin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a cephalosporin (eg, cephalexin) or other beta-lactam antibiotic (eg, imipenem)
  • if you have kidney problems, bleeding or clotting problems, or abnormal blood electrolyte levels, or if you are dehydrated
  • if you are on a low-salt diet

Some MEDICINES MAY INTERACT with ticarcillin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Tetracyclines (eg, doxycycline) because they may decrease ticarcillin's effectiveness
  • Anticoagulants (eg, warfarin) because their effectiveness may be decreased or the risk of their side effects may be increased by ticarcillin
  • Heparin or methotrexate because the risk of their side effects may be increased by ticarcillin
  • Aminoglycosides (eg, gentamicin) or oral contraceptives (eg, birth control pills) because their effectiveness may be decreased by ticarcillin

This may not be a complete list of all interactions that may occur. Ask your health care provider if ticarcillin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use ticarcillin:

Use ticarcillin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Ticarcillin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using ticarcillin at home, a health care provider will teach you how to use it. Be sure you understand how to use ticarcillin. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use ticarcillin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • To clear up your infection completely, use ticarcillin for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of ticarcillin, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use ticarcillin.

Important safety information:

  • Ticarcillin only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use ticarcillin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of ticarcillin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Ticarcillin may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Tell your doctor or dentist that you take ticarcillin before you receive any medical or dental care, emergency care, or surgery.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using ticarcillin. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Ticarcillin may interfere with certain lab test results. Be sure your doctor and lab personnel know you are using ticarcillin.
  • Lab tests, including kidney or liver function tests, complete blood cell counts, or blood electrolyte levels, may be performed while you use ticarcillin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use ticarcillin with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
  • PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using ticarcillin while you are pregnant. It is not known if ticarcillin is found in breast milk. If you are or will be breast-feeding while you use ticarcillin, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of ticarcillin:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Changes in taste and smell; diarrhea; gas; giddiness; headache; nausea; pain, swelling, or redness at the injection site; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; chest pain; dark urine; fever, chills, or sore throat; joint or muscle pain; red, swollen, or blistered skin; seizures; severe diarrhea; severe stomach pain/cramps; swelling in the mouth; unusual bruising or bleeding; unusual tiredness or weakness; vaginal irritation or discharge; vein swelling or tenderness; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; confusion; hallucinations; seizures; severe excitability; tremor; unconsciousness.

Proper storage of ticarcillin:

Ticarcillin is usually handled and stored by a health care provider. If you are using ticarcillin at home, store ticarcillin as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Do not store in the bathroom. Keep ticarcillin out of the reach of children and away from pets.

General information:

  • If you have any questions about ticarcillin, please talk with your doctor, pharmacist, or other health care provider.
  • Ticarcillin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about ticarcillin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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