Skip to main content


Generic name: infigratinib
Dosage form: capsules
Drug class: Multikinase inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on May 31, 2022.

What is Truseltiq?

Truseltiq is a prescription medicine used to treat adults with bile duct cancer (cholangiocarcinoma) that has spread or cannot be removed by surgery:

Your healthcare provider will test your cancer for certain FGFR2 gene abnormalities to make sure that Truseltiq is right for you.
It is not known if this medicine is safe and effective in children.

Before taking Truseltiq

Before you start treatment, tell your healthcare provider about all your medical conditions, including if you:

Females who can become pregnant:

Males with female partners who can become pregnant:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking Truseltiq with certain other medicines may affect how Truseltiq works.

Especially tell your healthcare provider if you take medicines used to decrease stomach acid and treat heartburn, called proton pump inhibitors (PPIs), H2 blockers, or antacids. You should avoid taking these medicines during treatment with Truseltiq. If you cannot avoid taking H2 blockers or antacids, see How should I take Truseltiq? for more information on how to take Truseltiq with these medicines.

How should I take Truseltiq?

Truseltiq side effects

Truseltiq may cause serious side effects, including:

The most common side effects include:

These are not all possible side effects. For more information, ask your healthcare provider or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Truseltiq?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Take your infigratinib dose 2 hours before or 10 hours after taking an "H2 blocker" stomach acid medicine. This includes cimetidine, famotidine, nizatidine, ranitidine, Pepcid, Tagamet, and Zantac.

Tell your doctor about any medicines you take to reduce stomach acid. This includes esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole, Nexium, and Prilosec.

Other drugs may interact with infigratinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

How should I store Truseltiq?

Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of Truseltiq.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information that is written for healthcare professionals.

What are the ingredients in Truseltiq?

Active ingredient: infigratinib phosphate
Inactive ingredients: colloidal silicon dioxide, crospovidone, hypromellose, lactose monohydrate, magnesium stearate (from vegetable source), and microcrystalline cellulose.
The capsule shells contain: black iron oxide, gelatin, red iron oxide, titanium dioxide, and yellow iron oxide.
The printing ink contains: black iron oxide, butyl alcohol, dehydrated alcohol, isopropyl alcohol, potassium hydroxide, propylene glycol, shellac, and strong ammonia solution.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.