Zilbrysq Side Effects
Generic name: zilucoplan
Medically reviewed by Drugs.com. Last updated on Dec 10, 2024.
Note: This document provides detailed information about Zilbrysq Side Effects associated with zilucoplan. Some dosage forms listed on this page may not apply specifically to the brand name Zilbrysq.
Applies to zilucoplan: parenteral injection for sub-q use.
Important warnings
This medicine can cause some serious health issues
REMS:
FDA approved a REMS for zilucoplan to ensure that the benefits outweigh the risks.
The REMS may apply to one or more preparations of zilucoplan and consists of the following: elements to assure safe use and implementation system.
See the FDA REMS page ([Web]) for specific information.
Side effects include:
Most common adverse effects (≥10%): injection site reactions, upper respiratory tract infection, diarrhea.
For healthcare professionals
Applies to zilucoplan: subcutaneous solution.
General adverse events
The most common adverse effects in at least 10% of patients were injection site reactions, upper respiratory tract infections, and diarrhea.[Ref]
Gastrointestinal
- Very common (10% or more): Diarrhea (11%)
- Common (1% to 10%): Nausea, vomiting
- Frequency not reported: Pancreatic events[Ref]
Pancreatic events included pancreatitis and pancreatic cysts.[Ref]
Genitourinary
- Common (1% to 10%): Urinary tract infection[Ref]
Local
- Very common (10% or more): Injection site reactions (29%)
Other
- Common (1% to 10%): Increased lipase, increased amylase
- Frequency not reported: Meningococcal infection, transient elevations of blood eosinophils[Ref]
Respiratory
- Very common (10% or more): Upper respiratory tract infections (14%)[Ref]
References
1. (2023) "Product Information. Zilbrysq (zilucoplan)." UCB Pharma Inc
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Further information
Zilbrysq side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
