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Xuriden Side Effects

Generic Name: uridine

Note: This document contains side effect information about uridine. Some of the dosage forms listed on this page may not apply to the brand name Xuriden.

For the Consumer

Applies to uridine: oral granule

Along with its needed effects, uridine (the active ingredient contained in Xuriden) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking uridine:

Incidence not known
  • Rash or itching skin

Some side effects of uridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Vomiting
Less common
  • Diarrhea
  • Nausea

For Healthcare Professionals

Applies to uridine: oral granule

Gastrointestinal

Very common (10% or more): Vomiting (10%)
Common (1% to 10%): Nausea, diarrhea[Ref]

General

-In 135 patients who had either received an overdose of fluorouracil or capecitabine or presented with severe or life-threatening toxicities within 96 hours, uridine (the active ingredient contained in Xuriden) triacetate was discontinued for adverse reactions in 2 patients; serious adverse reactions (Grade 3 nausea and vomiting) were seen in 1 patient.
-In 4 patients with hereditary orotic aciduria ranging in age from 3 to 19 years (3 males, 1 female) who received this drug for at least 9 months at dosages up to 120 mg/kg once a day, no adverse reactions were reported.[Ref]

References

1. "Product Information. Xuriden (uridine)." Wellstat Therapeutics Corp, Gaithersburg, MD.

2. "Product Information. Vistogard (uridine)." BTG International Inc, West Conshohocken, PA.

Some side effects of Xuriden may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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