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Wellcovorin Side Effects

Generic name: leucovorin

Medically reviewed by Drugs.com. Last updated on Feb 16, 2024.

Note: This document provides detailed information about Wellcovorin Side Effects associated with leucovorin. Some dosage forms listed on this page may not apply specifically to the brand name Wellcovorin.

Applies to leucovorin: powder for solution, solution, tablet.

Serious side effects of Wellcovorin

Along with its needed effects, leucovorin (the active ingredient contained in Wellcovorin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking leucovorin:

Rare side effects

Check with your doctor as soon as possible if any of the following side effects occur while taking leucovorin:

Rare side effects

- reported with use in treatment of cancer
  • convulsions (seizures)

For healthcare professionals

Applies to leucovorin: compounding powder, injectable powder for injection, injectable solution, oral tablet.

General adverse events

Adverse events attributed to use of leucovorin (the active ingredient contained in Wellcovorin) folinic acid by itself include allergic sensitization, including anaphylactoid reactions and urticaria; gastrointestinal and hematologic adverse events were common when used with fluorouracil.[Ref]

Gastrointestinal

When used with fluorouracil, diarrhea and dehydration have resulted in hospital admission and death.[Ref]

Hematologic

Hypersensitivity

Dermatologic

Other

Metabolic

Immunologic

Nervous system

Psychiatric

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2015) "Product Information. Leucovorin Calcium (leucovorin)." Epic Pharma LLC

Further information

Wellcovorin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.