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Voretigene Neparvovec Ophthalmic Side Effects

Medically reviewed by Drugs.com. Last updated on May 29, 2024.

Applies to voretigene neparvovec ophthalmic: intraocular suspension.

Important warnings This medicine can cause some serious health issues

Voretigene neparvovec can cause changes in your retina that could lead to vision loss. Talk to your doctor about the risks and benefits of this medicine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Voretigene neparvovec can cause changes in your retina that could lead to vision loss, including:

Talk to your doctor about the risks and benefits of this medicine.

Call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to voretigene neparvovec ophthalmic: intraocular suspension.

General adverse events

The most commonly reported adverse reactions have included eye redness, cataract, increased intraocular pressure, and retinal tear.[Ref]

Ocular

Ocular adverse reactions were reported in 66% (27/41) of subjects (46 out of 81 injected eyes; 57%). Adverse reactions may have been due to this drug, the subretinal injection procedure, the concomitant use of corticosteroids, or a combination of the all three.[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2018) "Product Information. Luxturna (voretigene neparvovec ophthalmic)." Spark Therapeutics, Inc.

Further information

Voretigene neparvovec ophthalmic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.