Tromethamine Side Effects
Medically reviewed by Drugs.com. Last updated on Jan 29, 2024.
Applies to tromethamine: intravenous solution.
Serious side effects of tromethamine
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
- Signs of high potassium levels like a heartbeat that does not feel normal; feeling confused; feeling weak, lightheaded, or dizzy; feeling like passing out; numbness or tingling; or shortness of breath.
- Trouble breathing, slow breathing, or shallow breathing.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Fever.
- This drug may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
Other side effects of tromethamine
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For healthcare professionals
Applies to tromethamine: compounding powder, intravenous solution.
Cardiovascular adverse events
- Frequency not reported: Chemical phlebitis, venospasms[Ref]
Dermatologic
- Frequency not reported: Extravasation tissue damage and sloughing[Ref]
Endocrine
- Frequency not reported: Transient depression of blood glucose[Ref]
Hepatic
- Frequency not reported: Hepatocellular necrosis[Ref]
Local
- Frequency not reported: Infection at site of injection, venous thrombosis or phlebitis from site of injection extravasation[Ref]
Metabolic
- Frequency not reported: Hypervolemia[Ref]
Other
- Frequency not reported: Febrile response[Ref]
Respiratory
- Frequency not reported: Ventilatory depression, respiratory depression[Ref]
References
1. (2001) "Product Information. Tham (tromethamine)." Abbott Pharmaceutical
More about tromethamine
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Further information
Tromethamine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.