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Tri-Luma Side Effects

Generic Name: fluocinolone / hydroquinone / tretinoin topical

Note: This document contains side effect information about fluocinolone / hydroquinone / tretinoin topical. Some of the dosage forms listed on this page may not apply to the brand name Tri-Luma.

For the Consumer

Applies to fluocinolone / hydroquinone / tretinoin topical: topical application cream

Along with its needed effects, fluocinolone / hydroquinone / tretinoin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fluocinolone / hydroquinone / tretinoin topical:

More common
  • Redness, peeling, drying, itching, or burning of the skin
Less common
  • Darkening of normal skin color
  • irritated skin
  • rash
Incidence not known
  • Blistering, crusting, or flaking of the skin
  • burning and itching of the skin with pinhead-sized red blisters
  • lightening of normal skin color
  • redness and scaling around the mouth
  • severe redness, soreness, or scaling of the skin
  • thinning of the skin with easy bruising

Some side effects of fluocinolone / hydroquinone / tretinoin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Blemishes on the skin
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • pimples
  • raised, dark red, wart-like spots on the skin

For Healthcare Professionals

Applies to fluocinolone / hydroquinone / tretinoin topical: topical cream

General

The most commonly reported side effects included erythema, desquamation, burning, and dryness.[Ref]

Dermatologic

Very common (10% or more): Erythema (up to 41%), desquamation (up to 38%), dryness (up to 14%), pruritus (up to 11%)
Common (1% to 10%): Acne, telangiectasia, rosacea, papules, acne-like rash, rash, vesicles, pigmentary changes
Postmarketing reports: Itching, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, secondary infection, skin atrophy, striae, miliaria, allergic contact dermatitis[Ref]

Nervous system

Very common (10% or more): Burning (18%)
Common (1% to 10%): Paresthesia[Ref]

Local

Common (1% to 10%): Irritation[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth[Ref]

References

1. "Product Information. Tri-Luma (fluocinolone / hydroquinone / tretinoin topical)." Galderma Laboratories Inc, Fort Worth, TX.

Some side effects of Tri-Luma may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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