Tetrahydrozoline ophthalmic Side Effects
For the Consumer
Applies to tetrahydrozoline ophthalmic: ophthalmic solution
Side effects include:
Ophthalmic: Blurred vision, irritation, mydriasis.
For Healthcare Professionals
Applies to tetrahydrozoline ophthalmic: compounding powder, ophthalmic solution
Systemic side effects are rare because of the minor extent of absorption after topical application.[Ref]
Ocular side effects have included blurred vision, irritation, mydriasis, conjunctival hyperemia, and blepharoconjunctivitis. Conjunctival application, especially when high concentrations have been used in the elderly, may liberate pigment granules, presumably from the iris.[Ref]
Nervous system side effects associated with ocular sympathomimetic agents have included headache, tremor, trembling, dizziness, nervousness, and drowsiness.[Ref]
Cardiovascular side effects have rarely included palpitations, hypertension, and bradycardia.[Ref]
1. "Product Information. Collyrium Fresh (tetrahydrozoline)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
2. Soparkar CN, Wilhelmus KR, Koch DD, Wallace GW, Jones DB "Acute and chronic conjunctivitis due to over-the-counter ophthalmic decongestants." Arch Ophthalmol 115 (1997): 34-8
It is possible that some side effects of tetrahydrozoline ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
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