Sars-cov-2 (covid-19) Mrna-lnp Vaccine (cvx 309) Side Effects
Applies to sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309): intramuscular suspension.
General adverse events
The most commonly reported side effects included injection site pain, fatigue, and headache.[Ref]
Cardiovascular
- Postmarketing reports: Myocarditis, pericarditis[Ref]
Dermatologic
- Frequency not reported: Hyperhidrosis, night sweats
- Postmarketing reports: Pruritus, rash, urticaria[Ref]
Gastrointestinal
- Very common (10% or more): Diarrhea (up to 11.1%)
- Common (1% to 10%): Vomiting
- Frequency not reported: Nausea[Ref]
Hematologic
- Common (1% to 10%): Lymphadenopathy[Ref]
Hypersensitivity
- Postmarketing reports: Anaphylaxis, angioedema, other hypersensitivity reactions (e.g., pruritus, rash, urticaria), severe allergic reactions[Ref]
Local
- Very common (10% or more): Injection site pain (up to 90.5%), injection site swelling (up to 11.8%), injection site redness (up to 10.4%)
- Postmarketing reports: Extremity (arm) pain[Ref]
Metabolic
- Frequency not reported: Decreased appetite[Ref]
Musculoskeletal
- Very common (10% or more): Chills (up to 49.2%), muscle pain (up to 45.5%), new/worsened muscle pain (up to 39.3%), joint pain (up to 27.5%), new/worsened joint pain (up to 23.8%)[Ref]
Nervous system
- Very common (10% or more): Headache (up to 75.5%)
- Frequency not reported: Bell's palsy/facial paralysis, lethargy
- Postmarketing reports: Dizziness, syncope[Ref]
Other
- Very common (10% or more): Fatigue (up to 77.5%), use of antipyretic or pain medication (up to 50.8%), fever (up to 24.3%)
- Frequency not reported: Asthenia, malaise[Ref]
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References
1. (2023) "Product Information. Comirnaty (2023-2024) PF (cvx 309) (SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 309))." Pfizer U.S. Pharmaceuticals Group
2. (2024) "Product Information. Comirnaty (2024-2025) PF (cvx 309) (SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 309))." Pfizer U.S. Pharmaceuticals Group
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Further information
Sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309) side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.