Provocholine Side Effects
Generic Name: methacholine
Note: This page contains side effects data for the generic drug methacholine. It is possible that some of the dosage forms included below may not apply to the brand name Provocholine.
For the Consumer
Applies to methacholine: inhalation solution
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking methacholine (the active ingredient contained in Provocholine)
Headache; itching; lightheadedness; throat irritation.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; cough; fainting; severe dizziness; wheezing.
For Healthcare Professionals
Applies to methacholine: compounding powder, inhalation powder for reconstitution
When administered orally or by injection, this drug is reported to cause nausea, vomiting, substernal pain or pressure, hypotension, fainting, and transient complete heart block. Overdosage with this drug, when administered orally or by injection, can result in a syncopal reaction with cardiac arrest and loss of consciousness. This drug should be administered only by inhalation.[Ref]
Very rare (less than 0.01%): Headache, lightheadedness[Ref]
Very rare (less than 0.01%): Itching[Ref]
Very rare (less than 0.01%): Throat irritation[Ref]
1. "Product Information. Provocholine (methacholine)." Methapharm Inc, Brantford, ON.
It is possible that some side effects of Provocholine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
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