Methacholine Pregnancy and Breastfeeding Warnings

Brand names: Provocholine

Methacholine Pregnancy Warnings

Use is not recommended.
According to some authorities, this drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus.

Risk summary: No data available on use of this drug in pregnant women to inform a drug-related risk.

US FDA pregnancy category: Not assigned

Comments:
-Use of bronchoprovocation challenge to diagnose bronchial airway hyperreactivity is not recommended during pregnancy because of the potential for hypoxia.
-Consider empiric treatment of suspected bronchial airway hyperreactivity instead.

Animal studies have not been conducted. There are no controlled data in human pregnancy.

US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.

See references

Methacholine Breastfeeding Warnings

Safety has not been established. This drug should be used only if benefits clearly outweigh the risks.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments:
-There is no information regarding this drug on the presence in human milk, the effects on a breastfed infant, or effects on milk production.
-Consider the developmental and health benefits of breastfeeding along with the mother's clinical need for this medication as well as any potential adverse effects from this drug or the underlying maternal condition.

See references

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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