Pralidoxime Side Effects
Medically reviewed by Drugs.com. Last updated on June 13, 2020.
For the Consumer
Applies to pralidoxime: injection powder for solution
Side effects requiring immediate medical attention
Along with its needed effects, pralidoxime may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking pralidoxime:
- Blurred or double vision
- change in near or distance vision
- difficult or rapid breathing
- difficulty in focusing the eyes
- difficulty with speaking
- fast, pounding, or irregular heartbeat or pulse
- muscle stiffness or weakness
- pain at the injection site (after injection into a muscle)
Incidence not known
- Deep or fast breathing with dizziness
- numbness of the feet, hands, and around the mouth
Side effects not requiring immediate medical attention
Some side effects of pralidoxime may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For Healthcare Professionals
Applies to pralidoxime: intravenous powder for injection
Frequency not reported: Muscular weakness[Ref]
Frequency not reported: Drowsiness[Ref]
Frequency not reported: Hyperventilation[Ref]
Frequency not reported: Blurred vision, diplopia, impaired accommodation[Ref]
Frequency not reported: Nausea[Ref]
Frequency not reported: Transient elevations of creatine phosphokinase
SGOT and SGPT levels returned to normal after about 2 weeks.[Ref]
Frequency not reported: Elevations in SGOT and/or SGPT enzymes[Ref]
Frequency not reported: Pain at the injection site[Ref]
Mild to moderate pain at the injection site occurs 40 to 60 minutes after intramuscular injection.[Ref]
1. "Product Information. Protopam Chloride (pralidoxime)." Baxter Healthcare Corporation, Deerfield, IL.
More about pralidoxime
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: antidotes
- FDA Alerts (1)
- Other brands
- Protopam Chloride
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.