Oxsoralen Side Effects

Generic Name: methoxsalen topical

Note: This page contains side effects data for the generic drug methoxsalen topical. It is possible that some of the dosage forms included below may not apply to the brand name Oxsoralen.

For the Consumer

Applies to methoxsalen topical: topical lotion

As well as its needed effects, methoxsalen topical (the active ingredient contained in Oxsoralen) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking methoxsalen topical, check with your doctor immediately:

• Blistering and peeling of skin
• reddened, sore skin
• swelling, especially of the feet or lower legs

There is an increased risk of developing skin cancer after use of methoxsalen. You should check the treated areas of your body regularly and show your doctor any skin sores that do not heal, new skin growths, and skin growths that have changed in the way they look or feel.

Premature aging of the skin may occur as a result of prolonged methoxsalen therapy. This effect is permanent and is similar to the result of sunbathing for long periods of time.

For Healthcare Professionals

Applies to methoxsalen topical: topical lotion, topical solution

General

Systemic adverse reactions have not been reported with methoxsalen topical (the active ingredient contained in Oxsoralen) ^[Ref]

Dermatologic

Dermatologic side effects have included mild to severe burns and blistering of the skin. The most common adverse reaction is severe burns of the treated area from overexposure to UVA, including sunlight.^[Ref]

It is possible that some side effects of Oxsoralen may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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