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Mydral Side Effects

Generic Name: tropicamide ophthalmic

Note: This page contains information about the side effects of tropicamide ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Mydral.

For the Consumer

Applies to tropicamide ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by tropicamide ophthalmic (the active ingredient contained in Mydral). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking tropicamide ophthalmic, check with your doctor or nurse as soon as possible:

Symptoms of too much medicine being absorbed into the body
  • Clumsiness or unsteadiness
  • confusion
  • fast heartbeat
  • flushing or redness of face
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • increased thirst or dryness of mouth
  • skin rash
  • slurred speech
  • swollen stomach in infants
  • unusual behavior, especially in children
  • unusual drowsiness, tiredness, or weakness

Minor Side Effects

Some of the side effects that can occur with tropicamide ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Blurred vision
  • headache
  • sensitivity of eyes to light
  • stinging of the eye when the medicine is applied

For Healthcare Professionals

Applies to tropicamide ophthalmic: compounding powder, ophthalmic solution


Side effects reported with this drug have included transient stinging, blurred vision, photophobia and superficial punctate keratitis. Some patients have experienced prolonged mydriasis.[Ref]


Frequency not reported: Headache, drowsiness, somnolence, fatigue, trouble concentrating, central nervous system disturbances, dysphonia
Postmarketing reports: Dizziness[Ref]


Frequency not reported: Psychotic reaction, behavioral disturbance[Ref]

Behavioral disturbances or psychotic reactions may be more common in children.[Ref]

Nervous system

Frequency not reported: Headache, drowsiness, somnolence, fatigue, trouble concentrating, central nervous system disturbances, dysphonia
Postmarketing reports: Dizziness[Ref]


Transient bradycardia followed by tachycardia with palpitations and arrhythmias have been reported.[Ref]

Frequency not reported: Tachycardia, bradycardia, arrhythmias, palpitations
Postmarketing reports: Hypotension, syncope[Ref]


Frequency not reported: Allergic reaction, anaphylaxis[Ref]


Frequency not reported: Dry mouth, thirst, dysphagia, nausea, vomiting, constipation[Ref]


Frequency not reported: Rhinitis, reduced bronchial secretions, bronchospasm
Postmarketing reports: Dryness of mucous membranes[Ref]


Frequency not reported: Urinary retention, difficult micturition[Ref]


Frequency not reported: Erythematous rash, pruritus, pallor, flushing, increased sweating, dry skin[Ref]


Frequency not reported: Muscle rigidity[Ref]


1. "Product Information. Tropicamide (tropicamide ophthalmic)." Bausch and Lomb, Rochester, NY.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for Mydral may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.