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Mumpsvax Side Effects

Generic name: mumps virus vaccine

Medically reviewed by Last updated on Jul 24, 2022.

Note: This document contains side effect information about mumps virus vaccine. Some dosage forms listed on this page may not apply to the brand name Mumpsvax.

Applies to mumps virus vaccine: subcutaneous powder for injection.


Local side effects have included burning/stinging at the injection site and wheal and flare.[Ref]


Hypersensitivity reactions have included anaphylaxis, anaphylactoid reactions, angioneurotic edema (including peripheral or facial edema), and bronchial spasm.[Ref]


Cardiovascular side effects have included vasculitis.[Ref]


Dermatologic side effects have included Stevens-Johnson Syndrome, erythema multiforme, and urticaria.[Ref]


Endocrine side effects have included diabetes mellitus.[Ref]


Genitourinary side effects have included orchitis.[Ref]


Gastrointestinal side effects have included pancreatitis; diarrhea, and parotitis.[Ref]


Hematologic side effects have included thrombocytopenia, purpura, lymphadenopathy, and leukocytosis.[Ref]

Nervous system

Although a causal relationship between the Urabe strain of mumps vaccine and aseptic meningitis has been shown, there are no data that associate the currently used Jeryl Lynn vaccine strain to aseptic meningitis.[Ref]

Nervous system side effects have included encephalitis, Guillain-Barré Syndrome (GBS), febrile seizures, ocular palsies, and aseptic meningitis.[Ref]


Ocular side effects have included optic neuritis, papillitis, retrobulbar neuritis, and conjunctivitis.[Ref]


Respiratory side effects have included cough and rhinitis.[Ref]


Otic side effects have included nerve deafness and otitis media.[Ref]

A postmarketing surveillance study in Finland during 1982 to 1993 with 1.5 million pediatric and adult vaccinees (measles/mumps/rubella vaccine) reported no deaths or permanent sequelae.[Ref]

Other side effects have included fever, syncope, and irritability.

Fatalities have been reported following administration of the polyvalent measles/mumps/rubella vaccine; however, causality has not been determined.

Health care providers should report any allergic or unusual adverse reactions to the Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967 (USA) and the manufacturer.[Ref]

More about Mumpsvax (mumps virus vaccine)

Patient resources

Related treatment guides


1. "Product Information. Mumpsvax (mumps virus vaccine)." Merck & Company Inc (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.