Methazolamide Side Effects
Medically reviewed by Drugs.com. Last updated on May 14, 2025.
Applies to methazolamide: oral tablets.
Side effects include:
Paresthesia, hearing dysfunction or tinnitus, fatigue, malaise, anorexia, altered taste, nausea, vomiting, diarrhea, polyuria, drowsiness, confusion.
For healthcare professionals
Applies to methazolamide: compounding powder, oral tablet.
Nervous system adverse events
- Frequency not reported: Paresthesias, hearing dysfunction or tinnitus, taste alteration, drowsiness, flaccid paralysis, convulsions[Ref]
Gastrointestinal
- Frequency not reported: Gastrointestinal disturbances, nausea, vomiting, diarrhea, melena[Ref]
Genitourinary
- Frequency not reported: Polyuria, glycosuria, crystalluria[Ref]
Metabolic
- Frequency not reported: Loss of appetite, metabolic acidosis, electrolyte imbalance[Ref]
Dermatologic
Other
- Frequency not reported: Fatigue, malaise[Ref]
Hepatic
- Frequency not reported: Hepatic insufficiency[Ref]
Immunologic
- Frequency not reported: Sulfonamide reactions[Ref]
Ocular
- Frequency not reported: Transient myopia[Ref]
Psychiatric
- Frequency not reported: Confusion[Ref]
Renal
- Frequency not reported: Renal calculi[Ref]
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References
1. (2006) "Product Information. Neptazane (methazolamide)." Wyeth-Ayerst Laboratories
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Further information
Methazolamide side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.