Joenja Side Effects
Generic name: leniolisib
Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.
Note: This document provides detailed information about Joenja.
Applies to leniolisib: oral tablets Side Effects associated with leniolisib. Some dosage forms listed on this page may not apply specifically to the brand name Joenja.
Applies to leniolisib: oral tablets.
Side effects include:
Most common adverse reactions (incidence >10%) reported with leniolisib (the active ingredient contained in Joenja) include headache, sinusitis, atopic dermatitis.
For healthcare professionals
Applies to leniolisib: oral tablet.
General adverse events
The most common adverse reactions included headache, sinusitis, and atopic dermatitis.[Ref]
Cardiovascular
- Very common (10% or more): Tachycardia/sinus tachycardia (10%)
Dermatologic
Gastrointestinal
Hematologic
Decreased neutrophil count (33%)
An absolute neutrophil count (ANC) between 500 and 1500 cells/mcL developed in 33% of patients during clinical studies. No patients developed an ANC less than 500 cells/mcL and there were no reports of infection associated with neutropenia.
Hypersensitivity
- Postmarketing reports: Hypersensitivity/anaphylaxis
Musculoskeletal
- Very common (10% or more): Back pain (10%), neck pain (10%)
Nervous system
- Very common (10% or more): Headache (up to 24%)
Other
- Very common (10% or more): Pyrexia (up to 19%), weight gain/increased (14%), otitis externa (14%), fatigue (10%)
Respiratory
- Very common (10% or more): COVID-19 (30%), upper respiratory tract infections (27%), sinusitis (up to 19%), respiratory tract infection (14%)
See also:
References
1. (2024) "Product Information. Joenja (leniolisib)." Pharming Technologies B.V.
2. (2025) "Product Information. Joenja (leniolisib)." Pharming Australia Pty Ltd
3. (2025) "Product Information. Joenja (leniolisib)." Pharming Healthcare Inc.
More about Joenja (leniolisib)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: PI3K inhibitors
- Breastfeeding
- En español
Patient resources
Professional resources
Related treatment guides
Further information
Joenja side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
