Hyperhep B Side Effects
Generic Name: hepatitis b immune globulin
Note: This page contains information about the side effects of hepatitis b immune globulin. Some of the dosage forms included on this document may not apply to the brand name Hyperhep B.
For the Consumer
Applies to hepatitis b immune globulin: solution
In addition to its needed effects, some unwanted effects may be caused by hepatitis b immune globulin (the active ingredient contained in Hyperhep B). In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking hepatitis b immune globulin, check with your doctor or nurse immediately:Rare
- Blurred vision
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
- difficult or labored breathing
- difficulty with swallowing
- fast heartbeat
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
Minor Side Effects
Some of the side effects that can occur with hepatitis b immune globulin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Back pain
- general feeling of discomfort
- muscle aches or pain
- pain at the injection site
- Abdominal or stomach cramping
- burning, heat, and redness at the injection site
- feeling as if you are going to vomit
- joint pain
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- cold sweats
- feeling cold
- flu-like symptoms
- upper abdominal or stomach pain
For Healthcare Professionals
Applies to hepatitis b immune globulin: injectable solution, intramuscular solution
Most side effects have been classified as mild.[Ref]
Local side effects have included erythema, pain, ecchymosis, and tenderness at the injection site.[Ref]
Hypersensitivity side effects including allergic reactions have been commonly reported. Urticaria, angioedema, and anaphylactic reactions have been reported rarely.[Ref]
Gastrointestinal side effects including nausea and vomiting have been commonly reported. Aphthous stomatitis, diarrhea, dyspepsia, and gingival hyperplasia have been reported in greater than 10% of patients.[Ref]
Other side effects have included fatigue (greater than 10%), peripheral edema (greater than 10%), pyrexia (greater than 10%), cold or flu symptoms (10%), lightheadedness (3%), fainting (3%), malaise, chills, and fever.[Ref]
Musculoskeletal side effects have been commonly reported. These have included back pain (greater than 10%), moderate low back pain, and arthralgia. Myalgia and joint stiffness have been reported.[Ref]
Hematologic side effects have included splenomegaly (greater than 10%) and decreased white blood cells.[Ref]
Hepatic side effects have included hepatobiliary disease (greater than 10%), increased AST, and alkaline phosphatase.[Ref]
Renal side effects have included nocturia (greater than 10%) and increased creatinine.[Ref]
Respiratory side effects including pleural effusion have been reported in greater than 10% of patients.
Dermatologic side effects including pruritus and rash have been reported in greater than 10% of patients.
Psychiatric side effects including agitation have been reported in greater than 10% of patients.
Immunologic side effects including liver transplant rejection, diarrhea infections, pneumonia, and sepsis have been reported in greater than 10% of patients.
Cardiovascular side effects including hypertension and hypotension have been reported in greater than 10% of patients.
Metabolic side effects have included hyperglycemia.
Nervous system side effects have included amnesia (greater than 10%), essential tremor (greater than 10%), and headache (6% to greater than 10%). At least two cases of tremor have been reported.
Ocular side effects including presbyopia have been reported in greater than 10% of patients.
1. "Product Information. Nabi-HB (hepatitis B immune globulin)." Allscripts Healthcare Solutions, Libertyville, IL.
2. "Product Information. Bayhep B (hepatitis B immune globulin)." Bayer Pharmaceutical Inc, West Haven, CT.
Not all side effects for Hyperhep B may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Hyperhep B (hepatitis b immune globulin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
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- En Español
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- Drug class: immune globulins
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