Exondys 51 Side Effects

Generic Name: eteplirsen

Note: This document contains side effect information about eteplirsen. Some of the dosage forms listed on this page may not apply to the brand name Exondys 51.

For the Consumer

Applies to eteplirsen: intravenous solution

Along with its needed effects, eteplirsen (the active ingredient contained in Exondys 51) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking eteplirsen:

More Common

• Loss of balance control
• vomiting

Some side effects of eteplirsen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence Not Known

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• blistering, burning, crusting, dryness, or flaking of the skin
• itching, scaling, severe redness, soreness, or swelling of the skin

For Healthcare Professionals

Applies to eteplirsen: intravenous solution

General

The more commonly reported adverse events have included balance disorder and vomiting.

Respiratory

Very common (10% or more): Upper respiratory tract infection^[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions including rash, urticaria, pyrexia, flushing, cough, dyspnea, bronchospasm, hypotension

Dermatologic

Very common (10% or more): Contact dermatitis (25%), contusion, facial flushing, transient erythema, excoriation, rash^[Ref]

Gastrointestinal

Very common (10% or more): Vomiting (38%)^[Ref]

Local

Very common (10% or more): Catheter site pain^[Ref]

Musculoskeletal

Very common (10% or more): Arthralgia^[Ref]

Nervous system

Very common (10% or more): Balance disorder (38%)^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Related questions

• What are the clinical benefits of Exondys 51?

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