Exondys 51 Side Effects
Generic name: eteplirsen
Medically reviewed by Drugs.com. Last updated on Feb 20, 2022.
Note: This document contains side effect information about eteplirsen. Some of the dosage forms listed on this page may not apply to the brand name Exondys 51.
For the Consumer
Applies to eteplirsen: intravenous solution
Side effects requiring immediate medical attention
Along with its needed effects, eteplirsen (the active ingredient contained in Exondys 51) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking eteplirsen:
More common
- Loss of balance control
- vomiting
Side effects not requiring immediate medical attention
Some side effects of eteplirsen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- blistering, burning, crusting, dryness, or flaking of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
For Healthcare Professionals
Applies to eteplirsen: intravenous solution
General
The more commonly reported adverse events have included balance disorder and vomiting.
Respiratory
Very common (10% or more): Upper respiratory tract infection[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity reactions including rash, urticaria, pyrexia, flushing, cough, dyspnea, bronchospasm, hypotension
Dermatologic
Very common (10% or more): Contact dermatitis (25%), contusion, facial flushing, transient erythema, excoriation, rash[Ref]
Gastrointestinal
Very common (10% or more): Vomiting (38%)[Ref]
Local
Very common (10% or more): Catheter site pain[Ref]
Musculoskeletal
Very common (10% or more): Arthralgia[Ref]
Nervous system
Very common (10% or more): Balance disorder (38%)[Ref]
Frequently asked questions
More about Exondys 51 (eteplirsen)
- Dosage information
- During pregnancy
- Pricing & coupons
- En español
- Drug class: miscellaneous uncategorized agents
- FDA approval history
Patient resources
Professional resources
Related treatment guides
References
1. "Product Information. Exondys 51 (eteplirsen)." Sarepta Therapeutics (2016):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.