Eteplirsen Side Effects

Medically reviewed by Drugs.com. Last updated on Jan 24, 2025.

Applies to eteplirsen: intravenous solution.

Serious side effects of eteplirsen

Along with its needed effects, eteplirsen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking eteplirsen:

More common side effects

• loss of balance control
• vomiting

Other side effects of eteplirsen

Some side effects of eteplirsen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• blistering, burning, crusting, dryness, or flaking of the skin
• itching, scaling, severe redness, soreness, or swelling of the skin

For healthcare professionals

Applies to eteplirsen: intravenous solution.

General adverse events

The most commonly reported adverse events were balance disorder and vomiting.^[Ref]

Cardiovascular

• Postmarketing reports: Flushing^[Ref]

Dermatologic

• Very common (10% or more): Contact dermatitis (25%), rash, urticaria^[Ref]

Gastrointestinal

• Very common (10% or more): Vomiting (38%)^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions^[Ref]

Local

• Very common (10% or more): Catheter site pain
• Postmarketing reports: Cyanosis of the lips^[Ref]

Metabolic

• Postmarketing reports: Dehydration^[Ref]

Nervous system

• Very common (10% or more): Balance disorder (38%), headache^[Ref]

Respiratory

• Very common (10% or more): Cough
• Postmarketing reports: Bronchospasm^[Ref]

Other

• Postmarketing reports: Malaise, pyrexia, protein urine present^[Ref]

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Further information

Eteplirsen side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer