Eplontersen Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.
Applies to eplontersen: sub-q autoinjector.
Side effects include:
Comme adverse effects (≥9%): Decreased vitamin A, vomiting.
For healthcare professionals
Applies to eplontersen: subcutaneous solution.
General adverse events
The most frequently reported side effects included decreased vitamin A and vomiting.[Ref]
Cardiovascular
- Common (1% to 10%): Atrioventricular (AV) heart block
- Frequency not reported: Complete AV block
AV heart block included at least 1 case of complete AV block.
Gastrointestinal
- Common (1% to 10%): Vomiting
Genitourinary
- Common (1% to 10%): Proteinuria
Local
- Common (1% to 10%): Injection site reactions
Injection site reactions included erythema, pain, and pruritis.
Metabolic
- Very common: Decreased vitamin A (15%)
Decreased vitamin A included vitamin A deficiency and decreased vitamin A.
Ocular
- Common (1% to 10%): Blurred vision, cataract
See also:
Vyndamax
Vyndamax may be given to reduce death or hospitalization caused by heart problems in adults with ...
Vyndaqel
Vyndaqel (tafamidis meglumine) is a transthyretin stabilizer that may be given to reduce death or ...
Onpattro
Onpattro is used to treat polyneuropathy in adults with hereditary transthyretin-mediated ...
Tegsedi
Tegsedi (inotersen) is an RNA-targeting treatment that may be used to reduce the symptoms of ...
Amvuttra
Amvuttra is used to treat polyneuropathy associated with hereditary transthyretin-mediated ...
Wainua
Wainua (eplontersen) is used to treat polyneuropathy of hereditary transthyretin-mediated ...
Patisiran
Patisiran (brand name Onpattro) is an injectable treatment for polyneuropathy caused by hereditary ...
Vutrisiran
Vutrisiran (brand name Amvuttra) is used to treat nerve damage associated with hereditary ...
References
1. (2023) "Product Information. Wainua (eplontersen)." Astra-Zeneca Pharmaceuticals
More about eplontersen
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: miscellaneous metabolic agents
- Breastfeeding
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
Further information
Eplontersen side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
