Cyclopentolate / Phenylephrine Ophthalmic Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 17, 2025.
Applies to cyclopentolate / phenylephrine ophthalmic: ophthalmic solution.
Important warnings
This medicine can cause some serious health issues
You should not receive this medicine if you have untreated narrow-angle glaucoma.
Get emergency medical help if you have any of these signs of an allergic reaction while taking cyclopentolate / phenylephrine ophthalmic: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
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blurred vision, tunnel vision, or seeing halos around lights;
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eye pain;
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fast heart rate, severe headache, pounding in your neck or ears, anxiety;
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fever;
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little or no urinating;
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flushing (warmth, redness, or tingly feeling);
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severe constipation; or
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weak or shallow breathing.
Infants and children may be more likely to have side effects from cyclopentolate and phenylephrine ophthalmic. Tell the doctor if the child has:
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confusion, changes in behavior, hallucinations;
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speech problems, trouble recognizing people;
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restless or excited behavior;
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loss of balance or coordination;
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seizure (convulsions); or
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feeding problems or loss of appetite.
Common side effects may include:
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dry mouth, nose, or throat;
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decreased sweating; or
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sensitivity to sunlight.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
See also:
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Mydriacyl
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Cyclogyl
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Isopto Atropine
Isopto Atropine is used for pupillary dilation, refraction, assessment, uveitis
Cyclopentolate ophthalmic
Cyclopentolate ophthalmic is used for pupillary dilation, refraction, assessment, uveitis
Tropicamide ophthalmic
Tropicamide ophthalmic is used for organophosphate poisoning, pupillary dilation, refraction, assessment
Phenylephrine ophthalmic
Phenylephrine ophthalmic is used for eye redness, pupillary dilation
Atropine ophthalmic
Atropine ophthalmic is used for pupillary dilation, refraction, assessment, uveitis
More about cyclopentolate / phenylephrine ophthalmic
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Further information
Cyclopentolate/phenylephrine ophthalmic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.