Crinecerfont Side Effects

Medically reviewed by Drugs.com. Last updated on Apr 10, 2025.

Applies to crinecerfont: oral capsules, oral solution.

Side effects include:

Most common adverse reactions (≥4%) in adults: fatigue, headache, dizziness, arthralgia, back pain, decreased appetite, myalgia.

Most common adverse reactions (≥4%) in pediatric patients: headache, abdominal pain, fatigue, nasal congestion, epistaxis.

For healthcare professionals

Applies to crinecerfont: oral capsule, oral solution.

Gastrointestinal adverse events

• Very common (10% or more): Abdominal pain (up to 13%)
• Frequency not reported: dyspepsia, nausea, and vomiting^[Ref]

Hypersensitivity

• Frequency not reported: Throat tightness, angioedema, generalized rash^[Ref]

Immunologic

• Very common (10% or more): Decreased neutrophil count (up to 37%)^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia, arthralgia, back pain, myalgia^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 25%)
• Common (1% to 10%): Dizziness^[Ref]

Psychiatric

• Common (1% to 10%): Suicidal ideation
• Frequency not reported: Restlessness, apathy^[Ref]

Respiratory

• Common (1% to 10%): Nasal congestion, epistaxis^[Ref]

Metabolic

• Common (1% to 10%): Decreased appetite
• Frequency not reported: Acute adrenal insufficiency, adrenal crisis^[Ref]

Other

• Very common (10% or more): Fatigue (up to 25%)^[Ref]

See also:

Further information

Crinecerfont side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer