Cinryze Side Effects
Generic Name: C1 esterase inhibitor (human)
Note: This page contains information about the side effects of C1 esterase inhibitor (human). Some of the dosage forms included on this document may not apply to the brand name Cinryze.
Common side effects of Cinryze include: headache. Other side effects include: abdominal pain, nausea, vomiting, and muscle spasm. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to C1 esterase inhibitor (human): intravenous powder for solution
In addition to its needed effects, some unwanted effects may be caused by C1 esterase inhibitor (human). In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking C1 esterase inhibitor (human), check with your doctor or nurse immediately:More common:
- Chest pain
- head congestion
- hoarseness or other voice changes
- nausea and vomiting
- pain or tenderness around the eyes and cheekbones
- sore throat
- tightness of the chest
- trouble breathing
- Flushing or redness of the skin
- unusually warm skin
- difficulty with speaking
- difficulty with swallowing
- double vision
- fast heartbeat
- general tiredness and weakness
- inability to move the arms, legs, or facial muscles
- numbness or tingling in the face, arms, or legs
- pain, redness, or swelling in the arm or leg
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- slow speech
- trouble speaking, thinking, or walking
Minor Side Effects
Some of the side effects that can occur with C1 esterase inhibitor (human) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Abdominal or stomach pain
- Change in taste
- loss of taste
- pain at the catheter site
For Healthcare Professionals
Applies to C1 esterase inhibitor (human): intravenous kit, intravenous powder for injection
Respiratory side effects have included sinusitis, bronchitis, upper respiratory tract infection, and viral upper respiratory tract infection.[Ref]
Nervous system side effects have included headache.[Ref]
Musculoskeletal side effects have included limb injury, back pain, and pain in extremity.[Ref]
Dermatologic side effects have included pruritus.[Ref]
Cardiovascular side effects have included postmarketing reports of thrombotic events including deep vein thrombosis, myocardial infarction, and transient ischemic attack.[Ref]
1. "Product Information. Cinryze (complement C1 esterase inhibitor)." ViroPharma Incorporated, Exton, PA.
2. Gandhi PK, Gentry WM, Bottorff MB "Thrombotic events associated with C1 esterase inhibitor products in patients with hereditary angioedema: investigation from the United States Food and Drug Administration adverse event reporting system database." Pharmacotherapy 32 (2012): 902-9
Not all side effects for Cinryze may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Cinryze (C1 esterase inhibitor (human))
- Other brands: Berinert
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