Bylvay Side Effects

Generic name: odevixibat

Medically reviewed by Drugs.com. Last updated on Jun 29, 2024.

Note: This document provides detailed information about Bylvay.

Applies to odevixibat: oral capsule, oral pellet Side Effects associated with odevixibat. Some dosage forms listed on this page may not apply specifically to the brand name Bylvay.

Applies to odevixibat: oral capsule, oral pellet.

Precautions

It is very important that your doctor check your or your child's progress at regular visits to see if the medicine is working properly and to decide if you should continue to take it. Blood tests may be needed to check for any unwanted effects.

This medicine may cause diarrhea. If you have any questions or if diarrhea continues or gets worse, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Bylvay

Along with its needed effects, odevixibat (the active ingredient contained in Bylvay) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking odevixibat:

More common side effects

• clay-colored stools
• confusion
• dark urine
• decreased urination
• diarrhea
• dizziness
• dry mouth
• fainting
• fever
• headache
• increased heart rate
• lightheadedness
• loss of appetite
• nausea
• rapid breathing
• skin rash
• stomach pain, fullness, or tenderness
• sunken eyes
• swelling of the feet or lower legs
• thirst
• unusual tiredness or weakness
• vomiting
• wrinkled skin
• yellow eyes or skin

Less common side effects

• fracture

For healthcare professionals

Applies to odevixibat: oral capsule, oral pellet.

General adverse events

The most commonly reported side effects included diarrhea, increased transaminases, vomiting, and abdominal pain.^[Ref]

Gastrointestinal

• Very common (10% or more): Diarrhea (up to 39.1%), vomiting (up to 17.4%), abdominal pain (up to 15.8%)^[Ref]

Hepatic

• Very common (10% or more): Increased transaminases (ALT, AST) (up to 21.1%), increased blood bilirubin (up to 13%)
• Common (1% to 10%): Cholelithiasis^[Ref]

Metabolic

• Very common (10% or more): Fat-soluble vitamin deficiency (vitamin A, D, E) (up to 15.8%)
• Common (1% to 10%): Dehydration^[Ref]

Hematologic

• Very common (10% or more): Splenomegaly (up to 10.5%)^[Ref]

Musculoskeletal

• Common (1% to 10%): Fracture^[Ref]

See also:

Further information

Bylvay side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer