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Bylvay Side Effects

Generic name: odevixibat

Medically reviewed by Last updated on Aug 12, 2023.

Note: This document contains side effect information about odevixibat. Some dosage forms listed on this page may not apply to the brand name Bylvay.

Applies to odevixibat: oral capsule, oral pellet.

Serious side effects of Bylvay

Along with its needed effects, odevixibat (the active ingredient contained in Bylvay) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking odevixibat:

More common

Less common

For Healthcare Professionals

Applies to odevixibat: oral capsule, oral pellet.


The most commonly reported side effects included diarrhea, increased transaminases, vomiting, and abdominal pain.[Ref]


Very common (10% or more): Diarrhea (up to 39.1%), vomiting (up to 17.4%), abdominal pain (up to 15.8%)[Ref]


Very common (10% or more): Increased transaminases (ALT, AST) (up to 21.1%), increased blood bilirubin (up to 13%)

Common (1% to 10%): Cholelithiasis[Ref]


Very common (10% or more): Fat-soluble vitamin deficiency (vitamin A, D, E) (up to 15.8%)

Common (1% to 10%): Dehydration[Ref]


Very common (10% or more): Splenomegaly (up to 10.5%)[Ref]


Common (1% to 10%): Fracture[Ref]


1. Product Information. Bylvay (odevixibat). Albireo Pharma, Inc. 2021.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.