BayHep B Side Effects
Generic Name: hepatitis b immune globulin
Note: This document contains side effect information about hepatitis b immune globulin. Some of the dosage forms listed on this page may not apply to the brand name BayHep B.
For the Consumer
Applies to hepatitis b immune globulin: solution
Along with its needed effects, hepatitis b immune globulin (the active ingredient contained in BayHep B) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking hepatitis b immune globulin:
- Blurred vision
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
Incidence Not Known
- difficult or labored breathing
- difficulty with swallowing
- fast heartbeat
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
Some side effects of hepatitis b immune globulin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Back pain
- general feeling of discomfort
- muscle aches or pain
- pain at the injection site
- Abdominal or stomach cramping
- burning, heat, and redness at the injection site
- feeling as if you are going to vomit
- joint pain
Incidence Not Known
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- cold sweats
- feeling cold
- flu-like symptoms
- upper abdominal or stomach pain
For Healthcare Professionals
Applies to hepatitis b immune globulin: injectable solution, intramuscular solution
Most side effects have been classified as mild.[Ref]
Gastrointestinal side effects including nausea and vomiting have been commonly reported. Aphthous stomatitis, diarrhea, dyspepsia, and gingival hyperplasia have been reported in greater than 10% of patients.[Ref]
Other side effects have included fatigue (greater than 10%), peripheral edema (greater than 10%), pyrexia (greater than 10%), cold or flu symptoms (10%), lightheadedness (3%), fainting (3%), malaise, chills, and fever.[Ref]
Musculoskeletal side effects have been commonly reported. These have included back pain (greater than 10%), moderate low back pain, and arthralgia. Myalgia and joint stiffness have been reported.[Ref]
Hematologic side effects have included splenomegaly (greater than 10%) and decreased white blood cells.[Ref]
Hepatic side effects have included hepatobiliary disease (greater than 10%), increased AST, and alkaline phosphatase.[Ref]
Renal side effects have included nocturia (greater than 10%) and increased creatinine.[Ref]
Respiratory side effects including pleural effusion have been reported in greater than 10% of patients.
Dermatologic side effects including pruritus and rash have been reported in greater than 10% of patients.
Psychiatric side effects including agitation have been reported in greater than 10% of patients.
Cardiovascular side effects including hypertension and hypotension have been reported in greater than 10% of patients.
Metabolic side effects have included hyperglycemia.
Nervous system side effects have included amnesia (greater than 10%), essential tremor (greater than 10%), and headache (6% to greater than 10%). At least two cases of tremor have been reported.
Ocular side effects including presbyopia have been reported in greater than 10% of patients.
1. "Product Information. Nabi-HB (hepatitis B immune globulin)." Allscripts Healthcare Solutions, Libertyville, IL.
2. "Product Information. Bayhep B (hepatitis B immune globulin)." Bayer Pharmaceutical Inc, West Haven, CT.
Some side effects may not be reported. You may report them to the FDA.