Skip to Content

BayHep B Side Effects

Generic name: hepatitis b immune globulin

Medically reviewed by Last updated on Mar 1, 2021.

Note: This document contains side effect information about hepatitis b immune globulin. Some of the dosage forms listed on this page may not apply to the brand name BayHep B.

For the Consumer

Applies to hepatitis b immune globulin: solution

Side effects requiring immediate medical attention

Along with its needed effects, hepatitis b immune globulin (the active ingredient contained in BayHep B) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking hepatitis b immune globulin:


  • Blurred vision
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • sweating
  • unusual tiredness or weakness

Incidence not known

  • Chills
  • cough
  • difficult or labored breathing
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • fever
  • hives
  • itching
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shortness of breath
  • skin rash
  • tightness in the chest
  • wheezing

Side effects not requiring immediate medical attention

Some side effects of hepatitis b immune globulin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

  • Abdominal or stomach cramping
  • burning, heat, and redness at the injection site
  • diarrhea
  • feeling as if you are going to vomit
  • joint pain

Incidence not known

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • cold sweats
  • feeling cold
  • flu-like symptoms
  • upper abdominal or stomach pain

For Healthcare Professionals

Applies to hepatitis b immune globulin: injectable solution, intramuscular solution


Common (1% to 10%): Hypotension

Postmarketing reports: Sinus tachycardia[Ref]


Postmarketing reports: Anaphylactoid reaction, hypersensitivity[Ref]


Common (1% to 10%): Nausea

Postmarketing reports: Abdominal pain upper, lipase increased[Ref]

Nervous system

Postmarketing reports: Dizziness, headache[Ref]


Postmarketing reports: Chills, feeling cold, influenza like illness, pyrexia[Ref]


Postmarketing reports: Back pain[Ref]


Postmarketing reports: Transaminases increased[Ref]


Postmarketing reports: Dyspnea[Ref]


Postmarketing reports: Cold sweat[Ref]

More about BayHep B (hepatitis b immune globulin)

Consumer resources

Other brands
Hyperhep B, Nabi-HB, HepaGam B, HepaGam B NovaPlus, Nabi-HB Novaplus

Professional resources

Related treatment guides


1. "Product Information. HepaGam B (hepatitis B immune globulin)." Cangene bioPharma, Inc., Baltimore, MD.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.