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Aphrodyne Side Effects

Generic name: yohimbine

Note: This document contains side effect information about yohimbine. Some of the dosage forms listed on this page may not apply to the brand name Aphrodyne.

Applies to yohimbine: compounding powder, oral tablet

Nervous system

Nervous system side effects have included excitation, increased motor activity, tremor, and dizziness.[Ref]


Cardiovascular side effects have included elevation in blood pressure and increase in heart rate.[Ref]


Gastrointestinal side effects have included nausea and vomiting, commonly reported after parenteral administration of yohimbine (the active ingredient contained in Aphrodyne) [Ref]


Psychiatric side effects have included irritability and generalized anxiety.[Ref]


General side effects have included headache and increase in sweating.[Ref]


Dermatologic side effects have included skin flushing reported with oral administration.[Ref]


A severe case of Raynaud's phenomenon has been reported in a 65-year-old man diagnosed with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia). Painful episodes which affected all toes and fingers and his penis lasted 10 to 15 minutes and were relieved with heat. Symptoms resolved slowly over time upon discontinuation of yohimbine (the active ingredient contained in Aphrodyne) Upon rechallenge with yohimbine, the patient developed more severe Raynaud's phenomenon.[Ref]

Medically reviewed by Last updated on Jul 10, 2021.

More about Aphrodyne (yohimbine)

Professional resources

Related treatment guides


1. "Product Information. Yocon (yohimbine)." Glenwood Inc, Tenafly, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.