Antivenin (micrurus fulvius) Side Effects
For the Consumer
Applies to antivenin (micrurus fulvius): intravenous kit, intravenous powder for solution
Along with its needed effects, antivenin (micrurus fulvius) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking antivenin (micrurus fulvius):
- Difficulty in breathing or swallowing
- itching, especially of feet or hands
- reddening of skin, especially around ears
- swelling of eyes, face, or inside nose
- unusual tiredness or weakness
For up to 24 days after you have received North American coral snake antivenin, you may develop symptoms of a side effect called serum sickness. The severity of the symptoms and the length of the sickness depend on the amount of North American coral snake antivenin you were given and how long the treatment lasted. During this period of time check with your doctor if you notice any of the following side effects:
- redness of joints
- skin rash and itching
- swollen glands
For Healthcare Professionals
Applies to antivenin (micrurus fulvius): intravenous kit
Hypersensitivity reactions have included immediate systemic reactions such as anaphylaxis and shock, characterized by apprehension, flushing, itching, urticaria, edema of the face, tongue, and throat, cough, dyspnea, cyanosis, vomiting, and collapse. Cardiac arrest and death have been reported with use of antivenin (Crotalidae) polyvalent (equine origin). Although it has not been reported for antivenin (Micrurus fulvius), because of the similarity of these products, this reaction cannot be ruled out for antivenin (Micrurus fulvius) (equine origin). Immediate hypersensitivity reactions occurred in <1% of patients with negative skin tests.
Serum sickness may occur 5 to 24 days after administration of antivenin. Symptoms may include fever, malaise, urticaria, lymphadenopathy, edema, arthralgia, nausea, vomiting, meningismus, peripheral neuritis, pain, muscle weakness, and permanent atrophy. Serum sickness may occur within less than 5 days, especially in patients who have previously received horse serum. Its frequency may be related to the number of vials the patient has received.[Ref]
Nervous system side effects have included meningismus, peripheral neuritis, pain, muscle weakness, and permanent atrophy.[Ref]
1. "Product Information. Antivenin (Micrurus Fulvius) (antivenin (Micrurus fulvius))." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Some side effects may not be reported. You may report them to the FDA.