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Antivenin (micrurus fulvius) Side Effects

Applies to antivenin (micrurus fulvius): intravenous kit


Hypersensitivity reactions have included immediate systemic reactions such as anaphylaxis and shock, characterized by apprehension, flushing, itching, urticaria, edema of the face, tongue, and throat, cough, dyspnea, cyanosis, vomiting, and collapse. Cardiac arrest and death have been reported with use of antivenin (Crotalidae) polyvalent (equine origin). Although it has not been reported for antivenin (Micrurus fulvius), because of the similarity of these products, this reaction cannot be ruled out for antivenin (Micrurus fulvius) (equine origin). Immediate hypersensitivity reactions occurred in <1% of patients with negative skin tests.

Serum sickness may occur 5 to 24 days after administration of antivenin. Symptoms may include fever, malaise, urticaria, lymphadenopathy, edema, arthralgia, nausea, vomiting, meningismus, peripheral neuritis, pain, muscle weakness, and permanent atrophy. Serum sickness may occur within less than 5 days, especially in patients who have previously received horse serum. Its frequency may be related to the number of vials the patient has received.[Ref]

Nervous system

Nervous system side effects have included meningismus, peripheral neuritis, pain, muscle weakness, and permanent atrophy.[Ref]


1. "Product Information. Antivenin (Micrurus Fulvius) (antivenin (Micrurus fulvius))." Wyeth-Ayerst Laboratories, Philadelphia, PA.

Some side effects of antivenin (micrurus fulvius) may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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