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Antivenin (Micrurus Fulvius) Dosage

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Venomous Snake Bite

Average dose: 3 to 5 vials
-Dose depends on response to treatment


Comments:
-Each reconstituted vial can neutralize approximately 2 mg Micrurus fulvius venom (approximately 250 mouse LD 50 [lethal dose]).

Use: Only for treatment of envenomation by North American coral snake (Micrurus, including eastern and Texas varieties)

Usual Pediatric Dose for Venomous Snake Bite

Adolescents: Average dose: to 5 vials
-Dose depends on response to treatment

Small children: Dose may be decreased, depending on response to treatment


Comments:
-Each reconstituted vial can neutralize approximately 2 mg Micrurus fulvius venom (approximately 250 mouse LD 50 [lethal dose]).

Use: Only for treatment of envenomation by North American coral snake (Micrurus, including eastern and Texas varieties)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
-Do not administer prophylactically to asymptomatic patients
-Hypersensitivity to horse serum, unless benefits outweigh risks and anaphylaxis management is readily available

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-For intravenous administration only.
-The manufacturer product information should be consulted for detailed administration instructions.

Storage requirements:
-Refrigerate; do not freeze

Reconstitution/preparation techniques:
-Reconstitute each vial with 10 mL sterile water for injection
-Do not shake
-Swirl for 1 minute every 5 minutes until complete dissolution
-Complete reconstitution takes at least 30 minutes
-Use within 4 hours of reconstitution.

IV compatibility:
-Sodium chloride

General:
-Determine if the patient is hypersensitive to horse serum.

Patient advice:
-Patients should contact a healthcare provider immediately if signs of delayed allergic reaction or serum sickness appear within 2 weeks of hospital discharge.
-Signs include rash, itching, joint pain, fever, lymphadenopathy, and malaise.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.