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Alphanine SD Side Effects

Generic Name: coagulation factor ix

Note: This document contains side effect information about coagulation factor ix. Some of the dosage forms listed on this page may not apply to the brand name Alphanine SD.

For the Consumer

Applies to coagulation factor ix: intravenous powder for solution

Along with its needed effects, coagulation factor ix (the active ingredient contained in Alphanine SD) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking coagulation factor ix:

Incidence not known
  • Anxiety
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain
  • confusion
  • cough
  • difficult or labored breathing
  • difficulty with swallowing
  • dizziness or lightheadedness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast heartbeat
  • hives, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • nausea
  • pains in the chest, groin, or legs, especially calves of the legs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • restlessness
  • severe headaches of sudden onset
  • sudden loss of coordination
  • sudden onset of shortness of breath for no apparent reason
  • sudden onset of slurred speech
  • sudden shortness of breath or troubled breathing
  • sudden vision changes
  • sweating
  • tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area
  • tightness in the chest
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusual tiredness or weakness
  • vomiting

Some side effects of coagulation factor ix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Change in taste
  • loss of taste
  • headache
  • pain in the arms or legs

For Healthcare Professionals

Applies to coagulation factor ix: intravenous kit, intravenous powder for injection

Hypersensitivity

Hypersensitivity side effects have included hypersensitivity reactions, including bronchospastic reactions and/or hypotension and anaphylaxis.[Ref]

Hematologic

Hematologic side effects have included and the development of high-titer inhibitors necessitating alternative treatments to factor IX replacement therapy.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.[Ref]

Dermatologic

Dermatologic side effects have included hives, rash, and flushing.[Ref]

Local

Local side effects have included Injection site reaction, Injection site pain, cellulitis at IV site, and phlebitis at IV site.[Ref]

Nervous system

Nervous system side effects have included headache, dizziness, taste perversion (altered taste), shaking, and drowsiness.[Ref]

Respiratory

Respiratory side effects have included dry cough, hypoxia, chest tightness, and dyspnea (respiratory distress)[Ref]

General

General side effects have included fever.[Ref]

Ocular

Ocular side effects have included blurred vision.[Ref]

Renal

Renal side effects have e included renal infarction.[Ref]

References

1. "Product Information. Alphanine SD (coagulation factor IX)." Grifols Biologicals Inc, Los Angeles, CA.

2. "Product Information. Mononine (coagulation factor IX)." CSL Behring, King of Prussia, PA.

3. "Product Information. BeneFIX (coagulation factor IX)." Wyeth Laboratories, Philadelphia, PA.

Some side effects of Alphanine SD may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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