Medically reviewed by Drugs.com. Last updated on Aug 7, 2020.
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- Aminobenzoate Potassium
- Potassium Aminobenzoate
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Potaba: 500 mg
Generic: 2 g (50 ea)
Brand Names: U.S.
- Vitamin, Water Soluble
P-aminobenzoate is a member of the vitamin B complex family. It may have an antifibrotic effect due to increased oxygen uptake at the tissue level.
Use: Labeled Indications
Presently, all indications are classified by the FDA as “possibly effective.”
Treatment of scleroderma, dermatomyositis, morphea, linear scleroderma, pemphigus, Peyronie's disease
Hypersensitivity to potassium p-aminobenzoate or any component of the formulation; concurrent use of sulfonamides
Oral: Average dose: 12 g/day in 4-6 divided doses
Refer to adult dosing.
Oral: 1 g/10 pounds of weight/day; administer in divided doses
All forms should be administered after meals or with a snack.
Capsule: Take with a glass of water.
Take with food to avoid stomach upset.
Sulfonamide Antibiotics: Potassium P-Aminobenzoate may diminish the therapeutic effect of Sulfonamide Antibiotics. Avoid combination
Frequency not defined.
Dermatologic: Skin rash
Gastrointestinal: Anorexia, nausea
Hypersensitivity: Hypersensitivity reaction
Concerns related to adverse effects:
• Anorexia: Interrupt therapy if anorexia occurs; may reinstitute once patient improves.
• Nausea: Interrupt therapy if nausea occurs; may reinstitute once patient improves.
• Diabetes: Use with caution in patients with diabetes mellitus or a history of hypoglycemia.
• Renal impairment: Use with caution in patients with renal impairment.
Safety for use in pregnancy has not been established.
What is this drug used for?
• It is used to treat autoimmune diseases.
• It is used to treat Peyronie's disease.
• It may be given to you for other reasons. Talk with the doctor.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
• Lack of appetite
• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
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