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Preparation H Cooling Gel (rectal)

Generic name: phenylephrine (rectal) [ FEN-il-EFF-rin-REK-tal ]
Brand names: Avedana Hemorrhoidal, Hemorrhoidal, Medicone Hemorrhoidal, Preparation H Cooling Gel, Preparation H Suppositories, ... show all 9 brands
Drug class: Anorectal preparations

Medically reviewed by Drugs.com on Aug 9, 2024. Written by Cerner Multum.

What is Preparation H Cooling Gel rectal?

Preparation H Cooling Gel is a decongestant that shrinks blood vessels. Dilated blood vessels can cause hemorrhoids.

Preparation H Cooling Gel is used on the rectum to relieve itching, burning, irritation, and swelling caused by hemorrhoids.

Preparation H Cooling Gel may also be used for purposes not listed in this medication guide.

Preparation H Cooling Gel rectal side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Preparation H Cooling Gel may cause serious side effects. Stop using Preparation H Cooling Gel and call your doctor at once if you have:

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Preparation H Cooling Gel if you are allergic to it Preparation H Cooling Gel (often used in certain cold or allergy medicines).

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

Always ask a doctor before using Preparation H Cooling Gel on a child. Do not give this medicine to a child younger than 2 years old.

How should I use Preparation H Cooling Gel rectal?

Use exactly as directed on the label, or as prescribed by your doctor.

You may use Preparation H Cooling Gel up to 4 times daily, especially after a bowel movement.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Do not place Preparation H Cooling Gel inside your rectum. The gel forms of phenylephrine rectal are for use only on the area around and just outside of your rectum.

Only the rectal suppository should be placed into the rectum.

Call your doctor if your symptoms do not improve after 7 days, or if they get worse.

Store at room temperature away from moisture and heat.

lidocaine topical, hydrocortisone topical, phenylephrine topical, Anusol-HC, benzocaine topical, zinc oxide topical

What happens if I miss a dose?

Since Preparation H Cooling Gel rectal is used on an as needed basis, you are not likely to miss a dose. Do not use Preparation H Cooling Gel more than 4 times per day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Preparation H Cooling Gel rectal?

Ask a doctor or pharmacist before using over-the-counter medicines that may contain ingredients similar to Preparation H Cooling Gel.

What other drugs will affect Preparation H Cooling Gel rectal?

Ask a doctor or pharmacist before using Preparation H Cooling Gel with any other medications, especially:

This list is not complete. Other drugs may affect Preparation H Cooling Gel, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Does Preparation H Cooling Gel interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.